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Case Report
Nelfinavir for COVID19: Summary of basic science data and initial clinical experience
Paul C Lee
Mount Sinai School of Medicine
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
Based on in vitro and computational model data that nelfinavir is highly active again SARS-CoV-2, we administered nelfinavir to six COVID-19 outpatients. Three of four acute outpatient COVID-19 patients became afebrile within 48 hours. In contrast, the two subacute COVID-19 patients with predominant GI symptoms responded only partially to nelfinavir.
Keywords
covid-19, SARS-CoV-2, nelfinavir, case series
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This is a preprint. It has not completed peer review.
Case Report
Nelfinavir for COVID19: Summary of basic science data and initial clinical experience
Paul C Lee
Mount Sinai School of Medicine
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 12 May, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Infectious Diseases
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Based on in vitro and computational model data that nelfinavir is highly active again SARS-CoV-2, we administered nelfinavir to six COVID-19 outpatients. Three of four acute outpatient COVID-19 patients became afebrile within 48 hours. In contrast, the two subacute COVID-19 patients with predominant GI symptoms responded only partially to nelfinavir.