The novel noninvasive pressure-strain loop (PSL) is a reliable tool that reflects myocardial work (MW). Systolic blood pressure (SBP) is the only independent factor for MW indices. However, afterload-related reference values have not been previously reported. The aim of the present study was to establish reference values for MW parameters by SBP grading over a wide range.
We prospectively selected healthy individuals and subjects with SBP ≥ 140mmHg at the time of study without myocardial remodeling. MW parameters were collected and the reference values achieved were grouped by SBP in 10-mmHg.
Significant differences were noted among the SBP-groups for global work index (GWI) and global constructive work (GCW). The majority of statistical comparisons of the differences in GWI and GCW were significant at each SBP-group. With SBP ranging from 90 to 189mmHg, the parameters GWI and GCW tended to increase linearly with afterload. Overall, the global wasted work (GWW) tended to rise as SBP was increased, but not all of the differences noted in GWW were significant for each SBP-group. Global work efficiency (GWE) remained stable across all SBP-groups, with the exception of a slight drop noted when it exceeded 160 mmHg.
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Posted 04 Mar, 2021
On 21 Mar, 2021
Received 15 Mar, 2021
Received 05 Mar, 2021
On 01 Mar, 2021
Received 01 Mar, 2021
Invitations sent on 01 Mar, 2021
On 01 Mar, 2021
On 27 Feb, 2021
On 27 Feb, 2021
On 24 Feb, 2021
On 24 Feb, 2021
Posted 04 Mar, 2021
On 21 Mar, 2021
Received 15 Mar, 2021
Received 05 Mar, 2021
On 01 Mar, 2021
Received 01 Mar, 2021
Invitations sent on 01 Mar, 2021
On 01 Mar, 2021
On 27 Feb, 2021
On 27 Feb, 2021
On 24 Feb, 2021
On 24 Feb, 2021
The novel noninvasive pressure-strain loop (PSL) is a reliable tool that reflects myocardial work (MW). Systolic blood pressure (SBP) is the only independent factor for MW indices. However, afterload-related reference values have not been previously reported. The aim of the present study was to establish reference values for MW parameters by SBP grading over a wide range.
We prospectively selected healthy individuals and subjects with SBP ≥ 140mmHg at the time of study without myocardial remodeling. MW parameters were collected and the reference values achieved were grouped by SBP in 10-mmHg.
Significant differences were noted among the SBP-groups for global work index (GWI) and global constructive work (GCW). The majority of statistical comparisons of the differences in GWI and GCW were significant at each SBP-group. With SBP ranging from 90 to 189mmHg, the parameters GWI and GCW tended to increase linearly with afterload. Overall, the global wasted work (GWW) tended to rise as SBP was increased, but not all of the differences noted in GWW were significant for each SBP-group. Global work efficiency (GWE) remained stable across all SBP-groups, with the exception of a slight drop noted when it exceeded 160 mmHg.
Figure 1
Figure 2
Figure 3
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