Objective: To explore the pathological characteristics of lymph nodes around inferior mesenteric artery in rectal cancer, and to explore its risk factors and its impact on tumor staging.
Methods: Cases of rectal cancer patients underwent proctectomy surgery were collected in this study. Clinical features of patients, including gender, age, BMI, tumor size, pathological type, differentiation, nerve invasion, lymph nodes, tumor marker and pathological examinations were analyzed.
Results: A total of 485 cases were included in this study. There were 29 cases with IMA-LN metastasis, the metastasis rate was 5.98% (29/485). Positive IMA-LNs were associated with distance from anal verge, CEA, pathological type, differentiation, nerve invasion, T stage and N stage. Multivariate analysis showed that distance from anal verge, CEA level, differentiation, and T stage were independent risk factors for positive IMA-LNs.
Conclusion: Distance from anal verge, CEA level, differentiation, and T stage were independent risk factors for positive IMA-LNs. No skip metastasis occurred in IMA-LNs. We should choose the appropriate surgical methods to achieve better oncological results and reduce the incidence of postoperative complications.
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Posted 10 Mar, 2021
On 04 Apr, 2021
Received 22 Mar, 2021
Received 19 Mar, 2021
On 16 Mar, 2021
Received 14 Mar, 2021
On 13 Mar, 2021
On 13 Mar, 2021
Received 10 Mar, 2021
On 10 Mar, 2021
Invitations sent on 07 Mar, 2021
On 07 Mar, 2021
On 06 Mar, 2021
On 06 Mar, 2021
On 28 Feb, 2021
Posted 10 Mar, 2021
On 04 Apr, 2021
Received 22 Mar, 2021
Received 19 Mar, 2021
On 16 Mar, 2021
Received 14 Mar, 2021
On 13 Mar, 2021
On 13 Mar, 2021
Received 10 Mar, 2021
On 10 Mar, 2021
Invitations sent on 07 Mar, 2021
On 07 Mar, 2021
On 06 Mar, 2021
On 06 Mar, 2021
On 28 Feb, 2021
Objective: To explore the pathological characteristics of lymph nodes around inferior mesenteric artery in rectal cancer, and to explore its risk factors and its impact on tumor staging.
Methods: Cases of rectal cancer patients underwent proctectomy surgery were collected in this study. Clinical features of patients, including gender, age, BMI, tumor size, pathological type, differentiation, nerve invasion, lymph nodes, tumor marker and pathological examinations were analyzed.
Results: A total of 485 cases were included in this study. There were 29 cases with IMA-LN metastasis, the metastasis rate was 5.98% (29/485). Positive IMA-LNs were associated with distance from anal verge, CEA, pathological type, differentiation, nerve invasion, T stage and N stage. Multivariate analysis showed that distance from anal verge, CEA level, differentiation, and T stage were independent risk factors for positive IMA-LNs.
Conclusion: Distance from anal verge, CEA level, differentiation, and T stage were independent risk factors for positive IMA-LNs. No skip metastasis occurred in IMA-LNs. We should choose the appropriate surgical methods to achieve better oncological results and reduce the incidence of postoperative complications.
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