Patient Data
For this retrospective study, we selected all patients who underwent PPV and SO injection for RRD from November 01, 2016 to November 30, 2019 at our department. A retrospective analysis was performed on all eyes that underwent 23-gauge PPV for RRD with SO injection.
Inclusion and Exclusion Criteria
Inclusion criteria included patients who were aged 18 years or older, those having a diagnosis of RRD, and the ability due to undergo PPV and SO injection for repair of retinal detachment.
Exclusion criteria included patients with a preoperative diagnosis of glaucoma, ocular hypertension, or another ocular disease that could alter IOP. Patients with RRD resulting from a macular hole or ocular trauma were also excluded.
Data Collection
Fifty-five patients underwent PPV and SO injection for RRD. Data of the last pre-operative visit and post-operative follow-up data on days 1, 3, and 6 were collected.
Surgical Technique
All surgical procedures were performed under local retrobulbar anesthesia by the same surgeon (LK. X.).
Standard 3-port PPV was performed 23-gauge instruments with a complete vitrectomy. The posterior retina was flattened with perfluorocarbon liquid. Then an air–fluid exchange with internal drainage of subretinal fluid. Retinopexy was achieved by laser coagulation. At the end of the procedure, air was exchanged with SO 5,000 centistokes. IOP at the end of surgery was adjusted to 15.0 ± 3.0 mmHg.
Four drops of each the topical steroids and the antibiotics were administered to all eyes daily and progressively tapered over a period of 4 weeks after surgery.
IOP Measurement
IOP was measured using a full auto tonometer (TX-F, Canon, Japan) in the preoperative period, on the first post-operative morning, and at 3 days and 6 days after surgery. An IOP ≥ 25 mmHg at any time during the post-operative period was considered IOP elevation. When the IOP was elevated during the post-operative period, antiglaucomatous medications were employed.
Statistical Analyses
Statistical analyses were performed with IBM SPSS Statistics for Windows, Version 26.0 (IBM Corp., Armonk, NY). Summary statistics included mean and standard deviation (SD) where appropriate. Categorical data were presented as percentages. A subset comparison was performed to analyze the differences between the operated and non-operated fellow eyes in the pre-operative periods using paired t-tests. Multivariable linear regression was used to assess the risk factors for postoperative IOP elevation. P-values < 0.05 were considered statistically significant.