Ethics approval and consent to participate
All study documents were reviewed and approved by the University of Washington Institutional Review Board (Protocol number: 00000472); a waiver of informed consent was obtained given minimal risks imposed to study participants.
Consent for publication
There are no individual person’s data provided in any form.
Data and Materials Availability
The datasets used and/or analyzed for the current study are available from the corresponding author on reasonable request. Templates used for the mailed FIT program materials and implementation workflow are available at the mailedfit.org website.
From September 2017 – June 2018, Kaiser Permanente Center for Health Research (Dr. Coronado served as the Principal Investigator) participated in an industry-funded study to compare the clinical performance of an experimental fecal immunochemical test (FIT) to an FDA-approved FIT. This study is funded by Quidel Corporation. From February 2016 to July 2018, Jennifer Coury was contracted with CareOregon, Inc. to improve colorectal cancer screening rates in health plan members, including coordination of a mailed FIT program. All other authors declare no competing interests.
This publication is a product of a Health Promotion and Disease Prevention Research Center grant supported by Cooperative Agreement Number U48DP005013 from the Centers for Disease Control and Prevention. The findings and conclusions in this publication are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.
JC was the lead author of the paper and led paper design and conception, assisted with data collection, contributed to interpretation of analysis results, and drafted initial and subsequent drafts of the manuscript. EJM conducted the configurational analysis in the study, contributed to interpretation of results, and helped write, review and edit the manuscript, especially sections related to the configurational analysis. PS coded and summarized source data to produce data for analysis and presentation, performed exploratory data analysis and wrote sections of paper pertaining to data summarization and exploratory analysis, produced figures and data for tabular summaries, and reviewed the paper. AP contributed to data collection, interpretation of analytical results, and helped write, review and edit the manuscript.
KC aided in the curation of primary data used for the study, and helped edit the manuscript as the primary contact for the health plan. BG and LMB contributed to the acquisition of financial support leading to this publication, analytic plan, to the interpretation of study results, and to review and editing of the article. JS contributed to the planning of the study, to the interpretation of study results, and to the review and editing of the manuscript. GC was the senior member of the research team and contributed to the acquisition of financial support leading to this publication, interpretation of study results and editing the article. All authors read and approved the final manuscript.
Thank you to Robin Daily for administrative support. The authors would like to acknowledge the clinic staff at all the organizations implementing the mailed FIT program for the perseverance during program roll-out.
JC is a Senior Research Associate at Oregon Health & Science University (OHSU) where she manages a body of research related to colorectal cancer in community health clinics. Prior to joining OHSU, JC managed the implementation of CareOregon’s mailed FIT program in partnership with collaborating health systems. She has over 20 years of experience working with evidence-based health care research, health communications, and practice implementation. GC is an epidemiologist who champions affordable, long-term solutions to health disparity issues. Her research portfolio includes several cost-effective interventions to improve rates of participation in cancer screening among patients served by community health centers. EM is an implementation researcher with expertise in mixed-methods evaluations of facility-level interventions and is a national expert in conducting research with Configurational Comparative Methods.