Breast cancer is the most prevalent cancer among women, and its chronic nature leads to long-term physiological and psychological effects that can significantly impact an individual's quality of life [7]. Various treatment approaches are employed to manage the disease, but they often come with debilitating side effects. Although advancements in health care, early detection, and treatment have improved survival rates, many patients still experience complications following treatment. While patients may appear to cope well with the stress of breast cancer treatment and maintain a normal life, the decline in physical well-being can affect their functional capacity. This is one of the first studies in the North Indian population to assess the quality of life in breast cancer patients after modified radical mastectomy, using the Functional Assessment of Cancer Therapy - General (FACT-G) questionnaire. A thorough review of the literature regarding Quality of life in breast cancer patients was done and the results are stated below. A cross-sectional, analytical, quantitative study was conducted previously in Brazil with one hundred participants, to assess the impact of breast cancer on the quality of life of women survivors and to identify any associations between sociodemographic and clinical variables. This study showed that the impact of the cancer scale predicted lower quality of life scores in several areas, including Body Changes, Negative Self-Evaluation, and Concerns about Cancer (p < 0.05). These findings suggest that breast cancer harmed the quality of life of women survivors, particularly in terms of body image changes, negative self-perception, and concerns related to the cancer diagnosis[8]. Another prospective study was conducted to investigate the quality of life and anxiety levels in patients with breast cancer and the changes they experience after receiving treatment using the Quality-of-Life Questionnaire (QLQ) C-30 and QLQ BR23 to assess the quality of life, and the State-Trait Anxiety Inventory (STAI) to measure anxiety levels indicated that the most distressing symptoms experienced by the patients were insomnia, fatigue, and concerns about hair loss. Following treatment, there was a worsening in the dimensions of physical function, role, body image, financial concerns, and symptoms. The highest levels of state anxiety at baseline were associated with being unmarried or widowed and the use of anxiolytic medication, an inactive work situation, and an advanced stage of breast cancer at diagnosis. After treatment, there was a positive modification in the quality-of-life scores, while state and trait anxiety levels were decreased [9]. Similarly, a study was conducted to examine the relationship between mental health (depression, anxiety, and stress), loneliness, illness perception, and health-related quality of life (HRQoL) in young breast cancer patients who underwent mastectomy within a year. The study also aimed to investigate the impact of breast reconstruction on these variables. The sample consisted of 81 women with stage II breast cancer, with 35 of them undergoing breast reconstruction and 46 without reconstruction. The researchers found that breast reconstruction was a significant predictor of overall Health-Related Quality of Life (HRQoL) and its domains. Women who underwent breast reconstruction exhibited better Health-Related Quality of Life (HRQoL), improved mental health, and lower stress and anxiety levels, but they experienced more physical discomfort and perceived a higher level of physical distress compared to those who did not undergo reconstruction. It is important to note that breast reconstruction alone is not a cure-all for improving Health-Related Quality of Life. Negative illness perceptions were associated with lower Health-Related Quality of Life for both groups [10]. Another study aimed to assess the quality of life (QOL) and symptom burden (SB) experienced by breast cancer patients with a total enrollment of 1513 patients with various stages of breast cancer, including ductal carcinoma in situ (DCIS), early-stage, locally advanced, or metastatic breast cancer. The participants completed the Edmonton Symptom Assessment System (ESAS) and the Functional Assessment of Cancer Therapy for Breast Cancer (FACT-B) questionnaires. The researchers found that patients who were 50 years old or younger and were 2–10 years post-treatment, as well as those who underwent chemotherapy or selective estrogen receptor modulator (SERM) treatment, experienced increased symptom burden and decreased quality of life. These findings suggest the need for individualized interventions and programs to address the physical, educational, and psychosocial needs of breast cancer patients across the continuum of care [11]. A systematic review aimed to investigate health-related quality of life in breast cancer patients from 2008 to 2018. The review followed the PRISMA guideline and identified a total of 974 relevant papers, of which 82 reviews were evaluated, focusing on the impact of treatments, including endocrine therapy, as well as the integration of complementary and alternative medicine into current practices. The findings from the reviews indicated that yoga was the most recommended exercise for improving the quality of life in breast cancer patients. Additionally, simple yet effective interventions such as physical activity and psychosocial interventions were found to be beneficial in enhancing the quality of life in this population. However, the management of symptoms such as pain and lymphedema, as well as issues related to worry and sexual function, particularly for younger patients, remained areas of concern [12]. A study conducted in the Chinese population to assess the quality of life in breast cancer patients showed higher scores in Physical Well-Being (PWB) were significantly associated with lower tumor stage. Social well-being (SWB) scores were significantly correlated with education and occupation, while lower Emotional Well-Being (EWB) was correlated with younger age and higher tumor stage [13]. Similarly, our study revealed that there was a statistically significant negative correlation between PWB and tumor stage (r = -0.90, p = 0.001). Strong positive correlations were observed between SWB and the education and occupation of the participants (r = 0.74, p = 0.003; r = 0.46, p = 0.013). Furthermore, a strong negative correlation was found between tumor stage and emotional well-being (r = 0.80, p = 0.0002). Participants in Group 3 had higher Physical, Social, and Emotional Well-Being Scores owing to surgical wound-related problems, and since this period usually passes in receiving adjuvant treatment. Our study indicates that breast cancer patients demonstrated effective coping mechanisms during their treatment journey. Patients after the first year of treatment were well recovered from physical, social and emotional domains, but the functional domains need time to recovery on contrary to previous studies conducted in American, Australian and Korean populations [14–17]. Additionally, this study found that cancer patients had a strong desire to learn more about their disease and expressed a need for tumor marker detection and PET scan. Our study echoes previous research, indicating that cancer patients desire more knowledge about their disease and seek tumor markers detection and PET scans. We observed that 64% of the patients faced limitations in their sexual relationships, and 23% of them experienced body image issues. These findings suggest that a significant number of breast cancer survivors encounter challenges in social, functional, and physical aspects of their lives. Prior studies have also highlighted a high prevalence of sexuality concerns among breast cancer survivors [18–21]. Possible reasons for this could be related to the impact of breast surgery on physical attractiveness and somatic issues, such as vaginal dryness resulting from cancer treatments like chemotherapy.