Surgical treatment plays a key role in the cure of gastric cancer. Our aim was to analyzed changes both in outcomes and in the epidemiology, over a time period of 15 years.
410 patients operated between January 2004 and December 2018 were enrolled. Patients were subdivided into 3 groups. The entire cohort was evaluated, and a more detailed analysys was made in patients that underwent a curative surgery. Survival outcomes and oncological surgical outcomes have been described and correlated with Overall Survival.
Results showed an increase trend in gastric cancer operation over the time period analyzed ( p< 0.05).Overall and disease free survival did not vary in the different time periods.
In patients treated with the intent to cure: 5- and 10-Year survivals were respectively: 44% and 34.7%; 5- and 10 years disease free survival were 50.7 and 49.4%. Type of lymphadenectomy and number of lymphondal harvested changed significantly over the time (p < 0.05).
Gastric surgery must be done in an experienced center to obtain oncological outcomes; in selected cases an extended lymphadenectomy could give survival benefit to patients with locally advanced gastric cancer.