Metastasis to lateral lymph nodes with no mesenteric lymph node involvement in low rectal cancer: a retrospective case series
Purpose The aim of this study is to examine the pattern of lymph node metastasis (lateral vs. mesenteric lymph nodes) in low rectal cancer.
Methods This retrospective analysis included all patients undergoing laparoscopic total mesorectal excision plus lateral lymph node dissection for advanced low rectal cancer (up to 8 cm from the anal verge) during a period from July 1, 2017 to August 31, 2019 at the Department of Colorectal Surgery, Tianjin Union Medical Center. The decision to conduct lateral lymph node dissection was based on positive findings in preoperative imaging assessments.
Results A total of 42 patients were included in data analysis. Surgery was successfully completed as planned, without conversion to open surgery in any case. A minimal of 10 mesenteric lymph nodes and 1 lateral lymph node on each side were dissected in all patients. Pathologic examination of resected specimens showed no metastasis to either mesenteric or lateral lymph nodes in 7 (16.7%) case, metastasis to both mesenteric and lateral lymph nodes in 26 (61.9%) cases, metastasis to mesenteric but not lateral lymph nodes in 4 (9.5%) cases, and metastasis to lateral but not mesenteric lymph nodes in 5 (11.9%) cases (n=2 in the obturator region; n=3 in the iliac artery region).
Conclusion A clinically significant proportion of low rectal cancer patients have metastasis to lateral lymph nodes without involvement of mesenteric lymph nodes. More carefully planned prospective studies are needed to verify this preliminary finding.
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Metastasis to lateral lymph nodes with no mesenteric lymph node involvement in low rectal cancer: a retrospective case series
On 06 Nov, 2020
On 26 Oct, 2020
On 14 Oct, 2020
On 13 Oct, 2020
On 13 Oct, 2020
On 07 Oct, 2020
On 04 Oct, 2020
Received 04 Oct, 2020
On 01 Oct, 2020
Invitations sent on 01 Oct, 2020
On 01 Oct, 2020
Received 01 Oct, 2020
On 30 Sep, 2020
On 30 Sep, 2020
On 09 Sep, 2020
Received 07 Sep, 2020
Received 05 Sep, 2020
Received 04 Sep, 2020
Received 02 Sep, 2020
Received 02 Sep, 2020
On 31 Aug, 2020
On 31 Aug, 2020
On 31 Aug, 2020
On 30 Aug, 2020
On 30 Aug, 2020
On 30 Aug, 2020
On 27 Aug, 2020
Invitations sent on 27 Aug, 2020
On 26 Aug, 2020
On 26 Aug, 2020
Posted 13 Aug, 2020
On 20 Aug, 2020
On 06 Aug, 2020
On 05 Aug, 2020
On 05 Aug, 2020
On 06 Jul, 2020
Received 02 Jul, 2020
Received 28 Jun, 2020
On 25 Jun, 2020
Received 25 Jun, 2020
Received 25 Jun, 2020
On 25 Jun, 2020
Received 25 Jun, 2020
Received 25 Jun, 2020
Received 25 Jun, 2020
Received 24 Jun, 2020
On 24 Jun, 2020
On 23 Jun, 2020
Received 22 Jun, 2020
On 20 Jun, 2020
Received 18 Jun, 2020
Received 18 Jun, 2020
Received 18 Jun, 2020
Received 18 Jun, 2020
Received 18 Jun, 2020
Received 18 Jun, 2020
On 17 Jun, 2020
On 17 Jun, 2020
On 17 Jun, 2020
On 17 Jun, 2020
On 17 Jun, 2020
On 17 Jun, 2020
On 17 Jun, 2020
On 16 Jun, 2020
On 16 Jun, 2020
On 11 Jun, 2020
Received 11 Jun, 2020
On 10 Jun, 2020
On 09 Jun, 2020
Invitations sent on 09 Jun, 2020
On 09 Jun, 2020
On 08 Jun, 2020
On 08 Jun, 2020
On 04 Jun, 2020
Purpose The aim of this study is to examine the pattern of lymph node metastasis (lateral vs. mesenteric lymph nodes) in low rectal cancer.
Methods This retrospective analysis included all patients undergoing laparoscopic total mesorectal excision plus lateral lymph node dissection for advanced low rectal cancer (up to 8 cm from the anal verge) during a period from July 1, 2017 to August 31, 2019 at the Department of Colorectal Surgery, Tianjin Union Medical Center. The decision to conduct lateral lymph node dissection was based on positive findings in preoperative imaging assessments.
Results A total of 42 patients were included in data analysis. Surgery was successfully completed as planned, without conversion to open surgery in any case. A minimal of 10 mesenteric lymph nodes and 1 lateral lymph node on each side were dissected in all patients. Pathologic examination of resected specimens showed no metastasis to either mesenteric or lateral lymph nodes in 7 (16.7%) case, metastasis to both mesenteric and lateral lymph nodes in 26 (61.9%) cases, metastasis to mesenteric but not lateral lymph nodes in 4 (9.5%) cases, and metastasis to lateral but not mesenteric lymph nodes in 5 (11.9%) cases (n=2 in the obturator region; n=3 in the iliac artery region).
Conclusion A clinically significant proportion of low rectal cancer patients have metastasis to lateral lymph nodes without involvement of mesenteric lymph nodes. More carefully planned prospective studies are needed to verify this preliminary finding.