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Research
Study on the Epidemiological Characteristics of SARS-CoV-2 Infection Based on Population of Zunyi, China
Daimin Xiao
Affiliated Hospital of Zunyi Medical University
Corresponding Author
Xun Min
Affiliated Hospital of Zunyi Medical University
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new type of virus that firstly confirmed in Wuhan, China recently. SARS-CoV-2 mainly spread through droplets. Infection characteristics data of SARS-CoV-2 is still limited, especially about asymptomatic infection, familial aggregation infection and infection risk in family member.
Methods
From 2nd January 2020 to 23th February 2020, we have screened 22,729 throat swab samples from individuals with either have contact history of imported personnel, out-of-city travel or residence history or flu-like symptoms during the past 14 days. SARS-CoV-2 RNA was extracted and detected by real-time PCR. Data were analyzed using SPSS version 19 (IBM, Armonk, NY, USA). The results were confirmed by the Pearson χ2 test; P ＜ 0.05 was considered statistically significant.
Results
35 SARS-CoV-2 positive patients were found, 22 were asymptomatic infection, and 31 were familial aggregation infection. Odds ratio of SARS-CoV-2 infection risk between family aggregated close contacts and overall close contacts was 29.40 (95％ confidence interval: 13.99 - 62.205, χ2 = 140.23, P ＜ 0.001); odds ratio of SARS-CoV-2 infection risk between family aggregated close contacts and non-family aggregated close contacts was 703.50 （95％ confidence interval: 89.53 - 5527.95, χ2 = 282.659, P ＜ 0.001). One SARS-CoV-2 positive patient infected 2.08 (25/12) people on average under social control without separate isolation.
Conclusions
Social control is effective in SARS-CoV-2 inhibition, but self-isolation and screening should be added as supplementary means to avoid familial aggregation infection and find out asymptomatic patients.
Keywords
SARS-CoV-2, Characteristics, Asymptomatic infection, Screening
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Research
Study on the Epidemiological Characteristics of SARS-CoV-2 Infection Based on Population of Zunyi, China
Daimin Xiao
Affiliated Hospital of Zunyi Medical University
Corresponding Author
Xun Min
Affiliated Hospital of Zunyi Medical University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 12 Jun, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Virology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new type of virus that firstly confirmed in Wuhan, China recently. SARS-CoV-2 mainly spread through droplets. Infection characteristics data of SARS-CoV-2 is still limited, especially about asymptomatic infection, familial aggregation infection and infection risk in family member.
Methods
From 2nd January 2020 to 23th February 2020, we have screened 22,729 throat swab samples from individuals with either have contact history of imported personnel, out-of-city travel or residence history or flu-like symptoms during the past 14 days. SARS-CoV-2 RNA was extracted and detected by real-time PCR. Data were analyzed using SPSS version 19 (IBM, Armonk, NY, USA). The results were confirmed by the Pearson χ2 test; P ＜ 0.05 was considered statistically significant.
Results
35 SARS-CoV-2 positive patients were found, 22 were asymptomatic infection, and 31 were familial aggregation infection. Odds ratio of SARS-CoV-2 infection risk between family aggregated close contacts and overall close contacts was 29.40 (95％ confidence interval: 13.99 - 62.205, χ2 = 140.23, P ＜ 0.001); odds ratio of SARS-CoV-2 infection risk between family aggregated close contacts and non-family aggregated close contacts was 703.50 （95％ confidence interval: 89.53 - 5527.95, χ2 = 282.659, P ＜ 0.001). One SARS-CoV-2 positive patient infected 2.08 (25/12) people on average under social control without separate isolation.
Conclusions
Social control is effective in SARS-CoV-2 inhibition, but self-isolation and screening should be added as supplementary means to avoid familial aggregation infection and find out asymptomatic patients.