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Research
CD4+ is associated with COVID-19-infected pneumonia patient recovery and recurrence
Bin Liu
The Affilated Hospital of Guangdong Medical University
Corresponding Author
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Coronavirus Disease 2019 (COVID-19)–infected pneumonia (CDIP) occurred in Wuhan, China, in December 2019, from where the disease has spread all over the world. Although the morbidity and mortality in China have been effectively controlled, the number of cases has increased rapidly in countries other than China. Here we report the epidemiological and clinical characteristics of 7 CDIP patients. We found that similar with the throat swabs, sputum induction still has a false negative rate. In addition, CD4+ count rise occurred before the disease remission, and decreased CD4+ count may be the cause of virus recurrence. These imply that CD4+ count could be a marker for recover and reinfection. Notably, we tentatively speculate that CD4+ plays a key role in the body's resistance to the COVID-19 attack on lung tissue.
Keywords
COVID-19, CD4+, recovery, recurrence
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This is a preprint. It has not completed peer review.
Research
CD4+ is associated with COVID-19-infected pneumonia patient recovery and recurrence
Bin Liu
The Affilated Hospital of Guangdong Medical University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 10 Jun, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Infectious Diseases
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Coronavirus Disease 2019 (COVID-19)–infected pneumonia (CDIP) occurred in Wuhan, China, in December 2019, from where the disease has spread all over the world. Although the morbidity and mortality in China have been effectively controlled, the number of cases has increased rapidly in countries other than China. Here we report the epidemiological and clinical characteristics of 7 CDIP patients. We found that similar with the throat swabs, sputum induction still has a false negative rate. In addition, CD4+ count rise occurred before the disease remission, and decreased CD4+ count may be the cause of virus recurrence. These imply that CD4+ count could be a marker for recover and reinfection. Notably, we tentatively speculate that CD4+ plays a key role in the body's resistance to the COVID-19 attack on lung tissue.
Figure 1