This preprint is under consideration at Annals of General Psychiatry. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
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Case report
Norio Yasui-Furukori
Dokkyo Ika Daigaku
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4414-3770
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
Takotsubo cardiomyopathy, also known as “apical ballooning syndrome”, is generally precipitated by endogenous or exogenous stress, and eating disorders have a variety of physical complications.
Case presentation
We present a case involving a 37-year-old Japanese female with eating disorders. She was admitted because of emaciation with shortness of breath and tiredness, and her weight was 30.0 kg (BMI 10.5 kg/m2) at this admission. On the afternoon of the first hospital day, a simple measurement caused hypoglycemia of 20 mg/dL, and she lost consciousness. On the night of the second hospital day, electrocardiogram showed negative T waves in II, III, aVf, and V1-6. Ultrasound echo showed hypokinesia at the apex of the heart and hypercontraction at the base of the heart. The left ventricular ejection fraction was 20%. Rest and oxygen administration gradually improved her cardiac function; the left ventricular ejection fraction also improved to 50% based on echocardiography. Finally, her weight increased by 43kg (BMI 15.2 kg/m2) with psychiatric treatment, and she was discharged.
Conclusions
The present case shows the clinical features of Takotsubo cardiomyopathy induced by a hypoglycemic event in addition to underlying anorexia nervosa.
Keywords
Takotsubo cardiomyopathy, hypoglycemia, anorexia nervosa, eating disorders
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CURRENT STATUS: Under Review
Version (no preprint)
Posted 23 Mar, 2021
This version was not preprinted
Version 1
Posted 23 Mar, 2021
No community comments so far
Editorial decision: Minor revision
On 21 Aug, 2021
Review #1 received
Received 17 Aug, 2021
Reviews received
Received 17 Aug, 2021
Reviewer #1 agreed
On 16 Aug, 2021
Reviewers invited
Invitations sent on 09 Apr, 2021
Editor assigned
On 18 Mar, 2021
Submission checks complete
On 18 Mar, 2021
Editor invited
On 18 Mar, 2021
First submitted
On 18 Mar, 2021
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HTML Views: ...
Subject Areas
Psychiatry
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This preprint is under consideration at Annals of General Psychiatry. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Case report
Norio Yasui-Furukori
Dokkyo Ika Daigaku
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4414-3770
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version (no preprint)
Posted 23 Mar, 2021
This version was not preprinted
Version 1
Posted 23 Mar, 2021
No community comments so far
Editorial decision: Minor revision
On 21 Aug, 2021
Review #1 received
Received 17 Aug, 2021
Reviews received
Received 17 Aug, 2021
Reviewer #1 agreed
On 16 Aug, 2021
Reviewers invited
Invitations sent on 09 Apr, 2021
Editor assigned
On 18 Mar, 2021
Submission checks complete
On 18 Mar, 2021
Editor invited
On 18 Mar, 2021
First submitted
On 18 Mar, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Psychiatry
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
Takotsubo cardiomyopathy, also known as “apical ballooning syndrome”, is generally precipitated by endogenous or exogenous stress, and eating disorders have a variety of physical complications.
Case presentation
We present a case involving a 37-year-old Japanese female with eating disorders. She was admitted because of emaciation with shortness of breath and tiredness, and her weight was 30.0 kg (BMI 10.5 kg/m2) at this admission. On the afternoon of the first hospital day, a simple measurement caused hypoglycemia of 20 mg/dL, and she lost consciousness. On the night of the second hospital day, electrocardiogram showed negative T waves in II, III, aVf, and V1-6. Ultrasound echo showed hypokinesia at the apex of the heart and hypercontraction at the base of the heart. The left ventricular ejection fraction was 20%. Rest and oxygen administration gradually improved her cardiac function; the left ventricular ejection fraction also improved to 50% based on echocardiography. Finally, her weight increased by 43kg (BMI 15.2 kg/m2) with psychiatric treatment, and she was discharged.
Conclusions
The present case shows the clinical features of Takotsubo cardiomyopathy induced by a hypoglycemic event in addition to underlying anorexia nervosa.
Figure 1
Figure 2
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