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Research article
Hemisensory Syndrome: Hyperacute symptom onset and age differentiates ischemic stroke from other aetiologies
Pei Xuan Koh
National Neuroscience Institute
Corresponding Author
ORCiD: https://orcid.org/0000-0002-8795-0177
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Background: An important cause of hemisensory syndrome is ischemic stroke. However, the diagnostic yield of neuroradiological imaging on hemisensory syndrome is low. Therefore, we aim to describe patients hospitalized with isolated hemisensory syndrome, and to identify clinical features associated with an aetiology of ischemic stroke.
Methods: We performed a single centre retrospective observation study, identifying patients who were hospitalised with hemisensory syndrome from October 2015 to March 2016, and whom underwent a magnetic resonance imaging (MRI) brain during the admission. Ischemic stroke was defined as the presence of restricted diffusion-weighted image on the MRI brain. Clinical information was analysed and compared between patients with and without stroke seen on MRI brain.
Results: Clinical features associated with ischemic stroke in hospitalised patients with hemisensory syndrome include symptom onset of ≤24 hours at presentation (odds ratio 31.4, 95% CI 3.89-254.4), advanced age (odds ratio 1.14, CI 1.05-1.25) and smoking (odds ratio 7.35, 95% CI 1.20-45).
Conclusion: Older patients, with a history of smoking, and who present with an acute onset of symptoms, are more likely to have ischemic stroke as the cause of their hemisensory syndrome.
Keywords
Hemisensory syndrome, ischemic stroke, numbness, magnetic resonance imaging
Figure 1
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CURRENT STATUS: Under Review
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Posted 17 Jun, 2020
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Review #1 received
Received 03 Jul, 2020
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On 01 Jun, 2020
Reviewer #2 agreed
On 01 Jun, 2020
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Editor assigned
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On 21 May, 2020
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Neurology
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This preprint is under consideration at BMC Neurology. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Hemisensory Syndrome: Hyperacute symptom onset and age differentiates ischemic stroke from other aetiologies
Pei Xuan Koh
National Neuroscience Institute
Corresponding Author
ORCiD: https://orcid.org/0000-0002-8795-0177
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 17 Jun, 2020
No community comments so far
Review #1 received
Received 03 Jul, 2020
Reviewer #1 agreed
On 01 Jun, 2020
Reviewer #2 agreed
On 01 Jun, 2020
Reviewers invited
Invitations sent on 29 May, 2020
Editor assigned
On 22 May, 2020
Submission checks complete
On 21 May, 2020
Editor invited
On 21 May, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Neurology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: An important cause of hemisensory syndrome is ischemic stroke. However, the diagnostic yield of neuroradiological imaging on hemisensory syndrome is low. Therefore, we aim to describe patients hospitalized with isolated hemisensory syndrome, and to identify clinical features associated with an aetiology of ischemic stroke.
Methods: We performed a single centre retrospective observation study, identifying patients who were hospitalised with hemisensory syndrome from October 2015 to March 2016, and whom underwent a magnetic resonance imaging (MRI) brain during the admission. Ischemic stroke was defined as the presence of restricted diffusion-weighted image on the MRI brain. Clinical information was analysed and compared between patients with and without stroke seen on MRI brain.
Results: Clinical features associated with ischemic stroke in hospitalised patients with hemisensory syndrome include symptom onset of ≤24 hours at presentation (odds ratio 31.4, 95% CI 3.89-254.4), advanced age (odds ratio 1.14, CI 1.05-1.25) and smoking (odds ratio 7.35, 95% CI 1.20-45).
Conclusion: Older patients, with a history of smoking, and who present with an acute onset of symptoms, are more likely to have ischemic stroke as the cause of their hemisensory syndrome.
Figure 1