This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Original investigation
Ferenc Petak
Szegedi Tudomanyegyetem Altalanos Orvostudomanyi Kar
Corresponding Author
ORCiD: https://orcid.org/0000-0001-6249-9327
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: To evaluate the monthly incidence rate of patients with diabetes requiring heart surgery at a tertiary-care university hospital in East-Central Europe with a temperate climate zone. We also assessed whether additional factors affecting small blood vessels (smoking, aging, and diabetes) modulate the seasonal variability of diabetes.
Methods: Medical records were retrospectively analyzed for all 9837 consecutive adult patients who underwent surgery at our institution between 2007 and 2018. Individual seasonal variations of diabetes, smoking, and elderly patients were analyzed monthly. Potential additive or subtractive effects of the coexistence of these factors in seasonal changes in incidence rates were also examined. In the absence of a waiting list, incidence rates accurately reflect the frequency of exacerbation of cardiovascular symptoms requiring surgical intervention.
Results: Significant seasonal variations in the monthly incidence rate of diabetes (p < 0.02), smoking (p < 0.001), and elderly (p < 0.001) patients were observed at the cardiac surgery unit. The peak incidence of non-elderly and smoking patients with diabetes was during winter, whereas heart surgery in elderly patients without diabetes and smoking was most frequently required in summer. Concomitant occurrence of diabetes and smoking had an additive effect on the relative incidence rate of requirement for cardiac surgery (p < 0.001), while the simultaneous presence of older age and diabetes or smoking eliminated seasonal variations.
Conclusions: Scheduling regular cardiovascular control in accordance with periodicities in diabetes, elderly, and smoking patients more than once a year may improve patient health and social consequences.
Trial registration: NCT03967639
Keywords
cardiovascular disease, cardiovascular surgery, T2DM, seasonality, cold weather
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Original investigation
Ferenc Petak
Szegedi Tudomanyegyetem Altalanos Orvostudomanyi Kar
Corresponding Author
ORCiD: https://orcid.org/0000-0001-6249-9327
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 22 Jun, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: To evaluate the monthly incidence rate of patients with diabetes requiring heart surgery at a tertiary-care university hospital in East-Central Europe with a temperate climate zone. We also assessed whether additional factors affecting small blood vessels (smoking, aging, and diabetes) modulate the seasonal variability of diabetes.
Methods: Medical records were retrospectively analyzed for all 9837 consecutive adult patients who underwent surgery at our institution between 2007 and 2018. Individual seasonal variations of diabetes, smoking, and elderly patients were analyzed monthly. Potential additive or subtractive effects of the coexistence of these factors in seasonal changes in incidence rates were also examined. In the absence of a waiting list, incidence rates accurately reflect the frequency of exacerbation of cardiovascular symptoms requiring surgical intervention.
Results: Significant seasonal variations in the monthly incidence rate of diabetes (p < 0.02), smoking (p < 0.001), and elderly (p < 0.001) patients were observed at the cardiac surgery unit. The peak incidence of non-elderly and smoking patients with diabetes was during winter, whereas heart surgery in elderly patients without diabetes and smoking was most frequently required in summer. Concomitant occurrence of diabetes and smoking had an additive effect on the relative incidence rate of requirement for cardiac surgery (p < 0.001), while the simultaneous presence of older age and diabetes or smoking eliminated seasonal variations.
Conclusions: Scheduling regular cardiovascular control in accordance with periodicities in diabetes, elderly, and smoking patients more than once a year may improve patient health and social consequences.
Trial registration: NCT03967639
Figure 1
Figure 2
Figure 3
This is a list of supplementary files associated with this preprint. Click to download.
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