Recycling underutilized resources from food waste (FW) to agriculture through hydrothermal carbonization (HTC) has been proposed to promote a circular economy in food, energy and water nexus. However, most HTC studies on FW have been conducted at laboratory scale, and little is known on efficacy of field application of HTC products from FW, i.e. aqueous product (AP) and solid hydrocharr(HC), to support agriculture production. To address these gaps, an integrated pilot-scale HTC system in this study is established to evaluate the reaction conditions and procedures for the HTC processing of FW. A peak temperature of 180 ℃ at a residence time of 60 minutes with 3 times recirculation of AP are recommended as the condition to achieve effective recovery of nutrients and water resources, and desirable AP and HC properties. Dilution of the raw AP and composting of the fresh HC eliminate potential phytotoxicity. Applying properly diluted AP and the composted HC can significantly improve plant growth and soil nutrient availability with comparable level to commercial fertilizer and soil amendment, respectively, in both greenhouse and field. The HTC treatment yields the most net negative carbon emission among common processing methods of FW and the direct potential profit. The current integrated pilot-scale study demonstrates that the HTC of FW and the agricultural application of its products have promising environmental advantages and economic feasibility.