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Research Article
Joung Hun Byun
Gyeongsang National University College of Medicine, Gyeongsang National University Changwon Hospital
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
We aimed to describe two factors (coronary artery tortuosity and bifurcation angle) as one descriptor for the evaluation of proximal left anterior descending coronary artery (LAD) disease. We reviewed the medical records of 133 consecutive patients who underwent computed tomography angiography (CTA) for angina symptoms in November 2019 and January 2020. The patients were divided into two groups according to the presence of significant LAD stenosis on CTA (defined as LAD stenosis > 50%). The straight length of the vessel was measured using the central luminal line of the flow path, and, calculated using proprietary algorithms in TeraRecon software. We used three-dimensional volume rendering and two-dimensional axial images to measure the left main coronary artery (LM)-LAD angles.
In the univariate analysis, there were significant differences in the linear distance between the endpoints of the 20mm actual curve of the LAD (d20), cosine value for LM-LAD angle (cosθ) < 0.8, age, presence of hypertension or diabetes, and number of pack years. However, in the multivariate analysis, the cosθ multiplied by the d20 (d20*cosθ) < 15.5, presence of hypertension and number of pack years were predictors of significant proximal LAD stenosis. In conclusion, d20*cosθ might be useful as a predictor of proximal LAD stenosis.
Keywords
coronary arteries, coronary artery disease, tortuosity, bifurcation
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No competing interests reported.
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research Article
Joung Hun Byun
Gyeongsang National University College of Medicine, Gyeongsang National University Changwon Hospital
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 12 Apr, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
We aimed to describe two factors (coronary artery tortuosity and bifurcation angle) as one descriptor for the evaluation of proximal left anterior descending coronary artery (LAD) disease. We reviewed the medical records of 133 consecutive patients who underwent computed tomography angiography (CTA) for angina symptoms in November 2019 and January 2020. The patients were divided into two groups according to the presence of significant LAD stenosis on CTA (defined as LAD stenosis > 50%). The straight length of the vessel was measured using the central luminal line of the flow path, and, calculated using proprietary algorithms in TeraRecon software. We used three-dimensional volume rendering and two-dimensional axial images to measure the left main coronary artery (LM)-LAD angles.
In the univariate analysis, there were significant differences in the linear distance between the endpoints of the 20mm actual curve of the LAD (d20), cosine value for LM-LAD angle (cosθ) < 0.8, age, presence of hypertension or diabetes, and number of pack years. However, in the multivariate analysis, the cosθ multiplied by the d20 (d20*cosθ) < 15.5, presence of hypertension and number of pack years were predictors of significant proximal LAD stenosis. In conclusion, d20*cosθ might be useful as a predictor of proximal LAD stenosis.
Figure 1
Figure 2
Figure 3
No competing interests reported.
This is a list of supplementary files associated with this preprint. Click to download.
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