Following the recent ideas of Guillen and Silvestre, we prove that the Fisher information is non-increasing along the flow of the isotropic Landau equation. We then use this fact to deduce global existence for the equation ∂tf = (−∆)−1f · ∆f + f2 under a relatively lax set of conditions on the initial data. In particular, we remove the restrictive radially decreasing assumption of previous works.