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The association of priori and posteriori dietary patterns with the risk of incident hypertension: Tehran Lipid and Glucose Study
Firoozeh Hosseini-Esfahani
Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0002-9697-0081
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The aim of this study was to investigate the association of dietary patterns with incident hypertension.
Materials/methods: This prospective study was conducted on 4793 individuals of Tehran lipid and glucose study participants, aged ≥18 years who were followed for a median of 6.3 years from 2008-11 to 2016-18. A valid and reliable semi-quantitative food frequency questionnaire was used to assess usual dietary intakes. Anthropometrics and blood pressure were assessed at baseline and during follow up examinations. Dietary patterns were derived using principal component analysis (PCA). Healthy eating index (HEI) and dietary approach to stop hypertension (DASH) score were measured based on dietary recommendations. Time-dependent Cox models adjusting for confounders were used to examine the association between dietary patterns and the risk of hypertension.
Results: During follow-up, a total of 727 incident cases of hypertension were identified. The mean±SD age at baseline was 40.3±13.5 and 37.9±12.1 years in men and women, respectively. Two dietary patterns (the healthy and unhealthy) were extracted by PCA. Compared with participants in the first quartile, a 23% (HR: 1.23; 95%CI: 1.00-1.53; P trend: 0.056) increased risk of hypertension was found in the fourth quartile of HEI score. This association was disappeared after further adjustment for confounders. Increasing DASH score, the healthy and unhealthy dietary pattern were not associated with risk of hypertension.
Conclusion: Our findings showed that higher adherences to the posteriori- and priori-dietary patterns were not associated with risk of hypertension in this population.
Keywords
blood pressure, hypertension, dietary pattern, healthy eating index, factor analysis, diet
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Received 02 Sep, 2020
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Received 31 Aug, 2020
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Received 25 Aug, 2020
Review #2 received
Received 25 Aug, 2020
Reviewer #7 agreed
On 21 Aug, 2020
Reviewer #8 agreed
On 21 Aug, 2020
Reviewer #9 agreed
On 21 Aug, 2020
Reviewer #6 agreed
On 20 Aug, 2020
Reviewer #5 agreed
On 18 Aug, 2020
Reviewers invited
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Reviewer #1 agreed
On 17 Aug, 2020
Reviewer #2 agreed
On 17 Aug, 2020
Reviewer #3 agreed
On 17 Aug, 2020
Reviewer #4 agreed
On 17 Aug, 2020
Editor assigned
On 07 Aug, 2020
Editor invited
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This preprint is under consideration at Journal of Translational Medicine. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
The association of priori and posteriori dietary patterns with the risk of incident hypertension: Tehran Lipid and Glucose Study
Firoozeh Hosseini-Esfahani
Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0002-9697-0081
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 3
Posted 04 Jan, 2021
No community comments so far
Review #2 received
Received 31 Dec, 2020
Review #1 received
Received 31 Dec, 2020
Reviewer #2 agreed
On 25 Dec, 2020
Reviewer #1 agreed
On 25 Dec, 2020
Reviewers invited
Invitations sent on 21 Dec, 2020
Editor assigned
On 18 Dec, 2020
Editor invited
On 18 Dec, 2020
Submission checks complete
On 18 Dec, 2020
No comments provided
Editorial decision: Major revision
On 19 Nov, 2020
Review #5 received
Received 18 Nov, 2020
Review #4 received
Received 17 Nov, 2020
Reviewer #5 agreed
On 11 Nov, 2020
Reviewer #4 agreed
On 11 Nov, 2020
Review #3 received
Received 10 Nov, 2020
Reviewer #3 agreed
On 09 Nov, 2020
Reviewer #2 agreed
On 08 Nov, 2020
Review #2 received
Received 08 Nov, 2020
Reviewer #1 agreed
On 06 Nov, 2020
Review #1 received
Received 06 Nov, 2020
Reviewers invited
Invitations sent on 05 Nov, 2020
Editor assigned
On 04 Nov, 2020
Submission checks complete
On 04 Nov, 2020
Editor invited
On 04 Nov, 2020
No comments provided
Review #7 received
Received 02 Sep, 2020
Editorial decision: Major revision
On 02 Sep, 2020
Review #6 received
Received 01 Sep, 2020
Review #4 received
Received 31 Aug, 2020
Review #5 received
Received 30 Aug, 2020
Review #3 received
Received 30 Aug, 2020
Review #1 received
Received 25 Aug, 2020
Review #2 received
Received 25 Aug, 2020
Reviewer #7 agreed
On 21 Aug, 2020
Reviewer #8 agreed
On 21 Aug, 2020
Reviewer #9 agreed
On 21 Aug, 2020
Reviewer #6 agreed
On 20 Aug, 2020
Reviewer #5 agreed
On 18 Aug, 2020
Reviewers invited
Invitations sent on 17 Aug, 2020
Reviewer #1 agreed
On 17 Aug, 2020
Reviewer #2 agreed
On 17 Aug, 2020
Reviewer #3 agreed
On 17 Aug, 2020
Reviewer #4 agreed
On 17 Aug, 2020
Editor assigned
On 07 Aug, 2020
Editor invited
On 06 Aug, 2020
Submission checks complete
On 25 Jul, 2020
First submitted
On 19 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Translational Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The aim of this study was to investigate the association of dietary patterns with incident hypertension.
Materials/methods: This prospective study was conducted on 4793 individuals of Tehran lipid and glucose study participants, aged ≥18 years who were followed for a median of 6.3 years from 2008-11 to 2016-18. A valid and reliable semi-quantitative food frequency questionnaire was used to assess usual dietary intakes. Anthropometrics and blood pressure were assessed at baseline and during follow up examinations. Dietary patterns were derived using principal component analysis (PCA). Healthy eating index (HEI) and dietary approach to stop hypertension (DASH) score were measured based on dietary recommendations. Time-dependent Cox models adjusting for confounders were used to examine the association between dietary patterns and the risk of hypertension.
Results: During follow-up, a total of 727 incident cases of hypertension were identified. The mean±SD age at baseline was 40.3±13.5 and 37.9±12.1 years in men and women, respectively. Two dietary patterns (the healthy and unhealthy) were extracted by PCA. Compared with participants in the first quartile, a 23% (HR: 1.23; 95%CI: 1.00-1.53; P trend: 0.056) increased risk of hypertension was found in the fourth quartile of HEI score. This association was disappeared after further adjustment for confounders. Increasing DASH score, the healthy and unhealthy dietary pattern were not associated with risk of hypertension.
Conclusion: Our findings showed that higher adherences to the posteriori- and priori-dietary patterns were not associated with risk of hypertension in this population.