See the published version of this preprint at BMC Family Practice.
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Learn more about In Review
Research article
Yuta Hirose
Chiba University Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4751-1065
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Patient awareness surveys on polypharmacy have been reported previously, but no previous study has examined the effects of sending feedback to health professionals on reducing medication use. Our study aimed to conduct a patient survey to examine factors contributing to polypharmacy, feedback the results to health professionals, and analyze the resulting changes in the number of polypharmacy patients and prescribed medications.
Methods: We conducted a questionnaire survey of patients in Study 1, while feedback of survey results health professionals, and before-after scrutiny of medical receipt data comprised polypharmacy in Study 2. In Study 1, we examined polypharmacy and its contributing factors by performing logistic regression analysis. In Study 2, we performe a t-test and a chi-square test.
Results: In the questionnaire survey, significant differences were found in the following 3 items: age (odds ratio (OR)=3.14; 95% confidence interval (CI)=2.01-4.91), number of medical institutions (OR=2.34; 95%CI=1.50-3.64), and patients' difficulty with asking their doctors to deprescribe their medications (OR=2.21; 95%CI=1.25-3.90). After the feedback, the percentage of polypharmacy patients decreased from 21.5% to 20.1% and the mean number of prescribed medications per patient decreased from 8.2 to 7.7 (p<0.001, respectively).
Conclusions: Providing feedback to health professionals on polypharmacy survey results may lead to a decrease in the number of polypharmacy patients. Factors contributing to polypharmacy included age (75 years or older), the number of medical institutions (2 or more institutions), and patients' difficulty with asking their physicians to deprescribe their medications. Feedback to health professionals reduced the percentage of polypharmacy patients and the number of prescribed medications.
Keywords
feedback, polypharmacy, questionnaire, health professions
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CURRENT STATUS: Published
View the published article at BMC Family Practice.
Version 2
Posted 05 Jan, 2021
No community comments so far
Editorial decision: Minor revision
On 18 Jan, 2021
Review #1 received
Received 03 Jan, 2021
Reviewers invited
Invitations sent on 16 Dec, 2020
Reviewer #1 agreed
On 16 Dec, 2020
Editor assigned
On 13 Dec, 2020
Submission checks complete
On 13 Dec, 2020
Editor invited
On 13 Dec, 2020
No comments provided
Editorial decision: Major revision
On 13 Nov, 2020
Review #2 received
Received 12 Nov, 2020
Reviewer #2 agreed
On 01 Sep, 2020
Review #1 received
Received 22 Aug, 2020
Reviewer #1 agreed
On 31 Jul, 2020
Reviewers invited
Invitations sent on 28 Jul, 2020
Editor assigned
On 13 Jul, 2020
Submission checks complete
On 12 Jul, 2020
Editor invited
On 12 Jul, 2020
First submitted
On 11 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
General Practice
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See the published version of this preprint at BMC Family Practice.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Yuta Hirose
Chiba University Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4751-1065
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Family Practice.
Version 2
Posted 05 Jan, 2021
No community comments so far
Editorial decision: Minor revision
On 18 Jan, 2021
Review #1 received
Received 03 Jan, 2021
Reviewers invited
Invitations sent on 16 Dec, 2020
Reviewer #1 agreed
On 16 Dec, 2020
Editor assigned
On 13 Dec, 2020
Submission checks complete
On 13 Dec, 2020
Editor invited
On 13 Dec, 2020
No comments provided
Editorial decision: Major revision
On 13 Nov, 2020
Review #2 received
Received 12 Nov, 2020
Reviewer #2 agreed
On 01 Sep, 2020
Review #1 received
Received 22 Aug, 2020
Reviewer #1 agreed
On 31 Jul, 2020
Reviewers invited
Invitations sent on 28 Jul, 2020
Editor assigned
On 13 Jul, 2020
Submission checks complete
On 12 Jul, 2020
Editor invited
On 12 Jul, 2020
First submitted
On 11 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
General Practice
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Family Practice.
Background: Patient awareness surveys on polypharmacy have been reported previously, but no previous study has examined the effects of sending feedback to health professionals on reducing medication use. Our study aimed to conduct a patient survey to examine factors contributing to polypharmacy, feedback the results to health professionals, and analyze the resulting changes in the number of polypharmacy patients and prescribed medications.
Methods: We conducted a questionnaire survey of patients in Study 1, while feedback of survey results health professionals, and before-after scrutiny of medical receipt data comprised polypharmacy in Study 2. In Study 1, we examined polypharmacy and its contributing factors by performing logistic regression analysis. In Study 2, we performe a t-test and a chi-square test.
Results: In the questionnaire survey, significant differences were found in the following 3 items: age (odds ratio (OR)=3.14; 95% confidence interval (CI)=2.01-4.91), number of medical institutions (OR=2.34; 95%CI=1.50-3.64), and patients' difficulty with asking their doctors to deprescribe their medications (OR=2.21; 95%CI=1.25-3.90). After the feedback, the percentage of polypharmacy patients decreased from 21.5% to 20.1% and the mean number of prescribed medications per patient decreased from 8.2 to 7.7 (p<0.001, respectively).
Conclusions: Providing feedback to health professionals on polypharmacy survey results may lead to a decrease in the number of polypharmacy patients. Factors contributing to polypharmacy included age (75 years or older), the number of medical institutions (2 or more institutions), and patients' difficulty with asking their physicians to deprescribe their medications. Feedback to health professionals reduced the percentage of polypharmacy patients and the number of prescribed medications.
Figure 1
This is a list of supplementary files associated with this preprint. Click to download.
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