Conventional magnetic resonance measurements often rely on the use of sample containers. This limits the implementation of time-resolved studies on the molecular level of liquid samples undergoing evaporation, phase transitions, or other dynamic phenomena. Previous attempts to study self-standing droplets in a magnetic field have predominantly focused on buoyancy forces of immiscible liquids[1–3], or molten aluminum beads studied by aerodynamic levitation[4–7]. However, these methods do not allow direct access to the interface and are restricted to non-volatile samples. Recent advancements have explored magnetic resonance studies on surface-resting sessile droplets[8, 9], providing real-time dynamic insights, yet, without granting a fully contact-free environment. In this study, we utilized a demagnetized acoustic levitator to perform magnetic resonance studies on liquid samples in a contact-free manner. Initially, we examined the performance of the levitator inside a 7.05 T magnetic field. Following, magnetic resonance images of the levitator and the levitated samples were acquired, acting as a direct proof of concept. Then, we collected magnetic resonance spectra of the levitated droplets by applying localized and non-localized pulse sequences, and we examined the effect of the droplet shape on the chemical shift. Additionally, we conducted time-resolved experiments on pure solvents and mixtures and captured physical and chemical molecular interactions in real time. This approach allows the implementation of real-time, dynamic, contact-free studies at the molecular level, on a microliter droplet, advancing the scope of magnetic resonance research.