As shown in the findings section above, an assessment of changes in HBA1 levels during the clinical trial period revealed a marginal increase from 4.889 at the start of the experiment to 4.985 at its end. This peripheral increase in HBA1 levels suggests a decrease in muscle mass - inferring the effectiveness of HPD on weight loss. However, given that the mode for the variable remained relatively constant throughout the trial period, it can be deduced that HPD was not as effective in changing HBA1 levels as it did insulin. However, the HPD diet had a negative effect on muscle mass, thereby underscoring its effectiveness in influencing weight loss programs.
In terms of insulin changes, there was a significant increase in mode from 7.8 at the start of the trial period to 9.3 during the completion stage. The findings suggest that the impact of the HPD on insulin resistance could have been masked by the marginal increases in mean values reported during the clinical trial. Overall, the increase in insulin levels among the patients, supported by differences in mode, suggests a significant increase in insulin levels during the trial period. Alternatively, based on the relationship between insulin and muscle bulk identified in the methodology section of this document, one could assume that the HPD had a negative effect on muscle mass. The implication of this finding on the research question is that HPD is effective in promoting favorable weight loss outcomes through inferred reductions in muscle mass. These findings imply that muscle loss is achievable after prolonged exposure to HPD [25].
Studies have supported the above-mentioned findings by re-affirming the effects of dietary effectiveness on weight loss [26]. Therefore, the findings generated have emphasized the importance of understanding the nutritional compounds of various dietary plans to comprehend their overall effectiveness [27]. Patients’ characteristics equally play an important role in determining the effectiveness of HPD programs. For example, some patients harbor a C-reactive compound in their genetic makeup, which may worsen, or improve, their metabolic reactions to HPD [28]. Such causative agents may lead to variations in muscle and skeletal mass during analysis [29].At the same time, certain population groups, such as older adults or people with pre-existing health conditions, may require high levels of protein intake owing to age-related factors [30]. For instance, studies have shown that the elderly have a significant risk of skeletal and muscle mass reduction owing to age-related factors [31]. Therefore, they may require a higher protein intake than the general population.
Most affiliated studies have taken a keen interest in understanding the impact of sex and age-related factors on weight loss programs. For example, women tend to lose skeletal muscle density faster than men [32]. This outcome remains consistent across various nutritional programs, including HPD [33]. However, scholars have used the Skeletal Mass Index (SMI) to investigate the effects of diets on weight loss programs. Their findings suggest that patients with low SMI are prone to several negative health outcomes, including low life expectancy and high rates of acute or chronic illnesses [34].Similarly, obesity may lead to lower bone density, while its effects further worsen with aging [35].Therefore, body mass gains lead to the deterioration of skeletal mass as a weight indicator [36 These statements suggest that the impact of HPD on weight loss could be moderated by patient’s demographic characteristics.
Subject to the influence of the above-mentioned effects of dietary interventions on weight loss, some strategies adopted by healthcare practitioners to manage obesity involve making changes to protein-based diets [37]. The same plan has been used to assess the effectiveness of protein-based diets on weight loss programs [38]. For example, researchers who have used nutritional interventions aimed at promoting body mass reductions through variations in protein levels have employed nitrogen balance as a key determinant of clinical effectiveness [39]. Their studies have had mixed results on obesity management.
An overview of the above limitations suggests that the HPD nutritional program may be associated with significant changes in body mass outcomes. These results are consistent with research showing that a HPD is associated with the preservation of lean body mass [40]. Therefore, one could argue that the emergence of HPD as an effective dietary plan for influencing weight reduction programs is consistent with extant literature.
The results highlighted in the findings section of this study revealed that the mean change for Vitamin D levels among the clinical trial group was 15.558 at the start to 15.345 in the end. Comparatively, out of all the three variables assessed in this investigation, changes in Vitamin D had the highest difference in mode. This statement means that there may have been significant differences in vitamin D response outcomes within the clinical trial group. However, they did not undermine the insignificance of the Vitamin D changes observed among the larger trial group after exposure to HPD.
The rise of the HPD in promoting the efficacy of nutritional intervention programs could create a paradigm shift in the use of protein-based nutritional plans in obesity management. Relative to this assertion, restrictions on calorie intake and intermediate fasting are equally important to this review but less effective in causing weight loss [41]. The effectiveness of HPD could be contrasted to past uses of the dietary method in clinical studies. Indeed, most researchers used it to suppress hunger and enhance satiety, as opposed to reducing body mass [42]. At the same time, researchers have used HPD to promote muscle mass growth and minimize fat gain by supporting the intake of protein-rich foods above the recommended daily intake levels [43]. Researchers who have highlighted the use of HPD this way have the opportunity to expand it to improve the effectiveness of programs designed to manage obesity [44]. Relative to these findings, HPD emerged as an effective dietary plan for weight loss treatment.