Designing the reasonable spiral structure and operating parameters of a vascular robot to improve the hemodynamic indicators is an important foundation for the non-invasive diagnosis and treatment of an interventional robot. This paper considers a pulsatile blood flow and an elastic blood vessel, and uses a bidirectional fluid structure interaction (FSI) method to numerically analyze the hemodynamic indicators such as blood flow velocity, blood pressure, vascular wall shear stress and vascular deformation under different spiral structures, translational speeds and rotational speeds of the interventional robot. Based on the particle image velocimetry (PIV) technology, the pulsating fluid flow field measurement system for the magnetic in-pipe robot was used to measure the fluid velocity around the robot during its precession. The results show that as the translational speed and rotational speed of the spiral robot are increased, the maximum blood pressure and the maximum deformation of the blood vessel are both slowly increased in a wavy manner. The average vascular wall shear stress is increased with the increase of the translational speed of the spiral robot, and the average vascular wall shear stress for the semicircular spiral robot is slightly greater than that for the triangular spiral robot. The distribution and magnitude of the calculated results are basically similar to those of the measured results.