See the published version of this preprint at BMC Surgery.
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Research article
Xiaocheng Zhu
Corresponding Author
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Background: To observe if absorbable suture can effectively and safely be used to close the mesenteric defect after Roux-en-Y reconstruction. Methods: Rats were randomly assigned to 5 experimental groups according to different suture materials used in closing the mesenteric defects (Peterson’s space) after Roux-en-Y gastric bypass. Group A (control group), Group B (non-absorbable suture, Prolene suture), Group C (biological glue), Group D (non-absorbable suture, polyester suture) and Group E (absorbable suture). All rats were followed up for 8 weeks postoperatively and underwent laparotomy to observe the degree of adhesion and closure of the mesenteric defect. Results: No significant difference was found in the decrease in food intake and body weight among all groups. No internal hernia (IH) occurred in any group. The mesenteric defects of Group A remained completely visible without any closure or adhesion. Multiple gaps were found between Prolene suture and the mesentery along the suture line in Group B. The mesenteric defects of Group C were complete closed with multiple adhesions of the small intestine and the greater omentum. The mesenteric defects had closed completely in both Group D and Group E. Average adhesion score of Group A and Group B was 0 and 0.33±0.52 respectively. Average adhesion score was higher in group C (3.83±0.41) than the other groups (p＜0.05). Group D and E had similar average adhesion score, 3.17±0.41 and 3.00±0.00 respectively. Conclusion: Absorbable sutures can be effectively and safely used to close the mesenteric defect in a rat model.
Keywords
mesenteric defect; peterson’s space; non-absorbable suture; absorbable suture
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CURRENT STATUS: Published
View the published article at BMC Surgery.
No community comments so far
Editorial decision: Accept
On 24 Dec, 2019
Editor assigned
On 23 Dec, 2019
Submission checks complete
On 22 Dec, 2019
Editor invited
On 22 Dec, 2019
No comments provided
Submission checks complete
On 17 Dec, 2019
Editorial decision: Minor revision
On 17 Dec, 2019
No comments provided
Editorial decision: Minor revision
On 12 Dec, 2019
Review #1 received
Received 24 Nov, 2019
Reviewers invited
Invitations sent on 15 Nov, 2019
Reviewer #1 agreed
On 15 Nov, 2019
Editor assigned
On 22 Oct, 2019
Submission checks complete
On 21 Oct, 2019
Editor invited
On 21 Oct, 2019
No comments provided
Editorial decision: Minor revision
On 20 Oct, 2019
Reviewer #1 agreed
On 11 Oct, 2019
Reviewer #2 agreed
On 11 Oct, 2019
Review #1 received
Received 11 Oct, 2019
Reviewers invited
Invitations sent on 10 Oct, 2019
Editor assigned
On 30 Sep, 2019
Submission checks complete
On 29 Sep, 2019
Editor invited
On 29 Sep, 2019
Version 1
Posted 04 Sep, 2019
No comments provided
Editorial decision: Major revision
On 18 Sep, 2019
Review #3 received
Received 17 Sep, 2019
Review #2 received
Received 15 Sep, 2019
Review #1 received
Received 15 Sep, 2019
Reviewer #3 agreed
On 07 Sep, 2019
Reviewers invited
Invitations sent on 05 Sep, 2019
Reviewer #1 agreed
On 05 Sep, 2019
Reviewer #2 agreed
On 05 Sep, 2019
Editor assigned
On 05 Sep, 2019
Submission checks complete
On 29 Aug, 2019
Editor invited
On 29 Aug, 2019
First submitted
On 23 Aug, 2019
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See the published version of this preprint at BMC Surgery.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Xiaocheng Zhu
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Surgery.
No community comments so far
Editorial decision: Accept
On 24 Dec, 2019
Editor assigned
On 23 Dec, 2019
Submission checks complete
On 22 Dec, 2019
Editor invited
On 22 Dec, 2019
No comments provided
Submission checks complete
On 17 Dec, 2019
Editorial decision: Minor revision
On 17 Dec, 2019
No comments provided
Editorial decision: Minor revision
On 12 Dec, 2019
Review #1 received
Received 24 Nov, 2019
Reviewers invited
Invitations sent on 15 Nov, 2019
Reviewer #1 agreed
On 15 Nov, 2019
Editor assigned
On 22 Oct, 2019
Submission checks complete
On 21 Oct, 2019
Editor invited
On 21 Oct, 2019
No comments provided
Editorial decision: Minor revision
On 20 Oct, 2019
Reviewer #1 agreed
On 11 Oct, 2019
Reviewer #2 agreed
On 11 Oct, 2019
Review #1 received
Received 11 Oct, 2019
Reviewers invited
Invitations sent on 10 Oct, 2019
Editor assigned
On 30 Sep, 2019
Submission checks complete
On 29 Sep, 2019
Editor invited
On 29 Sep, 2019
Version 1
Posted 04 Sep, 2019
No comments provided
Editorial decision: Major revision
On 18 Sep, 2019
Review #3 received
Received 17 Sep, 2019
Review #2 received
Received 15 Sep, 2019
Review #1 received
Received 15 Sep, 2019
Reviewer #3 agreed
On 07 Sep, 2019
Reviewers invited
Invitations sent on 05 Sep, 2019
Reviewer #1 agreed
On 05 Sep, 2019
Reviewer #2 agreed
On 05 Sep, 2019
Editor assigned
On 05 Sep, 2019
Submission checks complete
On 29 Aug, 2019
Editor invited
On 29 Aug, 2019
First submitted
On 23 Aug, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Surgery.
Background: To observe if absorbable suture can effectively and safely be used to close the mesenteric defect after Roux-en-Y reconstruction. Methods: Rats were randomly assigned to 5 experimental groups according to different suture materials used in closing the mesenteric defects (Peterson’s space) after Roux-en-Y gastric bypass. Group A (control group), Group B (non-absorbable suture, Prolene suture), Group C (biological glue), Group D (non-absorbable suture, polyester suture) and Group E (absorbable suture). All rats were followed up for 8 weeks postoperatively and underwent laparotomy to observe the degree of adhesion and closure of the mesenteric defect. Results: No significant difference was found in the decrease in food intake and body weight among all groups. No internal hernia (IH) occurred in any group. The mesenteric defects of Group A remained completely visible without any closure or adhesion. Multiple gaps were found between Prolene suture and the mesentery along the suture line in Group B. The mesenteric defects of Group C were complete closed with multiple adhesions of the small intestine and the greater omentum. The mesenteric defects had closed completely in both Group D and Group E. Average adhesion score of Group A and Group B was 0 and 0.33±0.52 respectively. Average adhesion score was higher in group C (3.83±0.41) than the other groups (p＜0.05). Group D and E had similar average adhesion score, 3.17±0.41 and 3.00±0.00 respectively. Conclusion: Absorbable sutures can be effectively and safely used to close the mesenteric defect in a rat model.
Figure 1
Figure 2
Figure 3
Figure 4
This is a list of supplementary files associated with this preprint. Click to download.
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