Background The mortality rates caused by SARS CoV-2 differ between countries and this difference might be explained by several reasons. Childhood vaccination rate is thought to be one of them. Therefore, present study aimed to examine the possible relationship between DTaP (diphtheria, tetanus, acellular pertussis vaccine) and measles vaccination rates of Organization for Economic Co-operation and Development (OECD) countries and case fatality rate (CFR) caused by SARS CoV-2.
Methods A total of 32 OECD countries, of northern hemisphere, have been included in this study. Statistical analysis performed according to the CFR data of these countries based on SARS CoV-2. The CFR data calculated according to the total mortality count of a specific country for the 3-month period down from the date when first SARS CoV-2 case was observed.
Results Based on the correlation levels of vaccination rates of OECD countries with a period of 3-month CFR, a strong negative correlation of significance between CFR and measles (r=-0.479, p=0.006) were pointed, while a negative but not significant correlation were seen between CFR and DTaP vaccination rates (r=-264.0, p=0.145).
Conclusion Depending on the results of the study, lower CFR based on COVID-19, is suggested to be related to the successful vaccination rates of those OECD countries. Therefore, further effort is required to improve rates of childhood vaccination not only for specified diseases, but either possible protection against COVID-19 worldwide.
Trial Registration: This study is registered to clinicaltrials.gov with trial number: NCT04468802.
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Posted 04 Aug, 2020
Received 07 Mar, 2021
On 07 Mar, 2021
On 09 Feb, 2021
Received 28 Sep, 2020
On 07 Sep, 2020
Invitations sent on 04 Sep, 2020
On 23 Jul, 2020
On 23 Jul, 2020
On 22 Jul, 2020
On 22 Jul, 2020
Posted 04 Aug, 2020
Received 07 Mar, 2021
On 07 Mar, 2021
On 09 Feb, 2021
Received 28 Sep, 2020
On 07 Sep, 2020
Invitations sent on 04 Sep, 2020
On 23 Jul, 2020
On 23 Jul, 2020
On 22 Jul, 2020
On 22 Jul, 2020
Background The mortality rates caused by SARS CoV-2 differ between countries and this difference might be explained by several reasons. Childhood vaccination rate is thought to be one of them. Therefore, present study aimed to examine the possible relationship between DTaP (diphtheria, tetanus, acellular pertussis vaccine) and measles vaccination rates of Organization for Economic Co-operation and Development (OECD) countries and case fatality rate (CFR) caused by SARS CoV-2.
Methods A total of 32 OECD countries, of northern hemisphere, have been included in this study. Statistical analysis performed according to the CFR data of these countries based on SARS CoV-2. The CFR data calculated according to the total mortality count of a specific country for the 3-month period down from the date when first SARS CoV-2 case was observed.
Results Based on the correlation levels of vaccination rates of OECD countries with a period of 3-month CFR, a strong negative correlation of significance between CFR and measles (r=-0.479, p=0.006) were pointed, while a negative but not significant correlation were seen between CFR and DTaP vaccination rates (r=-264.0, p=0.145).
Conclusion Depending on the results of the study, lower CFR based on COVID-19, is suggested to be related to the successful vaccination rates of those OECD countries. Therefore, further effort is required to improve rates of childhood vaccination not only for specified diseases, but either possible protection against COVID-19 worldwide.
Trial Registration: This study is registered to clinicaltrials.gov with trial number: NCT04468802.
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