This preprint is under consideration at BMC Public Health. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Ramazan Guven
Istanbul Kanuni Sultan Suleyman Egitim ve Arastirma Hastanesi
Corresponding Author
ORCiD: https://orcid.org/0000-0003-4129-8985
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background The mortality rates caused by SARS CoV-2 differ between countries and this difference might be explained by several reasons. Childhood vaccination rate is thought to be one of them. Therefore, present study aimed to examine the possible relationship between DTaP (diphtheria, tetanus, acellular pertussis vaccine) and measles vaccination rates of Organization for Economic Co-operation and Development (OECD) countries and case fatality rate (CFR) caused by SARS CoV-2.
Methods A total of 32 OECD countries, of northern hemisphere, have been included in this study. Statistical analysis performed according to the CFR data of these countries based on SARS CoV-2. The CFR data calculated according to the total mortality count of a specific country for the 3-month period down from the date when first SARS CoV-2 case was observed.
Results Based on the correlation levels of vaccination rates of OECD countries with a period of 3-month CFR, a strong negative correlation of significance between CFR and measles (r=-0.479, p=0.006) were pointed, while a negative but not significant correlation were seen between CFR and DTaP vaccination rates (r=-264.0, p=0.145).
Conclusion Depending on the results of the study, lower CFR based on COVID-19, is suggested to be related to the successful vaccination rates of those OECD countries. Therefore, further effort is required to improve rates of childhood vaccination not only for specified diseases, but either possible protection against COVID-19 worldwide.
Trial Registration: This study is registered to clinicaltrials.gov with trial number: NCT04468802.
Keywords
case fatality rate, SARS CoV-2, childhood vaccination
Loading...
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 04 Aug, 2020
No community comments so far
Review #2 received
Received 07 Mar, 2021
Editorial decision: Reject after review
On 07 Mar, 2021
Reviewer #2 agreed
On 09 Feb, 2021
Review #1 received
Received 28 Sep, 2020
Reviewer #1 agreed
On 07 Sep, 2020
Reviewers invited
Invitations sent on 04 Sep, 2020
First submitted
On 23 Jul, 2020
Editor assigned
On 23 Jul, 2020
Submission checks complete
On 22 Jul, 2020
Editor invited
On 22 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Learn more about our company.
This preprint is under consideration at BMC Public Health. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Ramazan Guven
Istanbul Kanuni Sultan Suleyman Egitim ve Arastirma Hastanesi
Corresponding Author
ORCiD: https://orcid.org/0000-0003-4129-8985
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 04 Aug, 2020
No community comments so far
Review #2 received
Received 07 Mar, 2021
Editorial decision: Reject after review
On 07 Mar, 2021
Reviewer #2 agreed
On 09 Feb, 2021
Review #1 received
Received 28 Sep, 2020
Reviewer #1 agreed
On 07 Sep, 2020
Reviewers invited
Invitations sent on 04 Sep, 2020
First submitted
On 23 Jul, 2020
Editor assigned
On 23 Jul, 2020
Submission checks complete
On 22 Jul, 2020
Editor invited
On 22 Jul, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background The mortality rates caused by SARS CoV-2 differ between countries and this difference might be explained by several reasons. Childhood vaccination rate is thought to be one of them. Therefore, present study aimed to examine the possible relationship between DTaP (diphtheria, tetanus, acellular pertussis vaccine) and measles vaccination rates of Organization for Economic Co-operation and Development (OECD) countries and case fatality rate (CFR) caused by SARS CoV-2.
Methods A total of 32 OECD countries, of northern hemisphere, have been included in this study. Statistical analysis performed according to the CFR data of these countries based on SARS CoV-2. The CFR data calculated according to the total mortality count of a specific country for the 3-month period down from the date when first SARS CoV-2 case was observed.
Results Based on the correlation levels of vaccination rates of OECD countries with a period of 3-month CFR, a strong negative correlation of significance between CFR and measles (r=-0.479, p=0.006) were pointed, while a negative but not significant correlation were seen between CFR and DTaP vaccination rates (r=-264.0, p=0.145).
Conclusion Depending on the results of the study, lower CFR based on COVID-19, is suggested to be related to the successful vaccination rates of those OECD countries. Therefore, further effort is required to improve rates of childhood vaccination not only for specified diseases, but either possible protection against COVID-19 worldwide.
Trial Registration: This study is registered to clinicaltrials.gov with trial number: NCT04468802.
Loading...