[1] Jeelani Y, Mosich GM, McComb JG. Closed neural tube defects in children with caudal regression. Childs Nerv Syst. 2013;29(9):1451-7.
[2] Aoulad Fares D, Schalekamp-Timmermans S, Nawrot TS, Steegers-Theunissen RPM. Preconception telomere length as a novel maternal biomarker to assess the risk of spina bifida in the offspring. Birth Defects Res. 2020,15;112(9):645-651.
[3] Wang S, Ji D, Yang Q, Li M, Ma Z, Zhang S, et al. NEFLb impairs early nervous system development via regulation of neuron apoptosis in zebrafish. J Cell Physiol. 2019;234(7):11208-11218.
[4] Geden MJ, Romero SE, Deshmukh M. Apoptosis versus axon pruning: Molecular intersection of two distinct pathways for axon degeneration.Neurosci Res. 2019;139:3-8.
[5] Abdallah MA, Ahmed KM, Recio-Restrepo MV, Khalid M, Yeddi A, Abu-Heija A, et al. Pneumococcal Meningitis Complicated by Spinal Cord Dysfunction and Acute Polyradiculopathy. Ochsner J. 2020;20(2):219-221.
[6] Kitada M, Dezawa M. Induction system of neural and muscle lineage cells from bone marrow stromal cells; a new strategy for tissue reconstruction in degenerative diseases. Histol Histopathol. 2009;24(5):631-42.
[7] Muench MO, Barcena A. Stem cell transplantation in the fetus. Cancer Control.
2004; 11: 105-18.
[8] Golchin A, Farahany TZ, Khojasteh A, Soleimanifar F, Ardeshirylajimi A. The Clinical Trials of Mesenchymal Stem Cell Therapy in Skin Diseases: An Update and Concise Review. Curr Stem Cell Res Ther. 2019;14(1):22-33.
[9] Myneni VD, McClain-Caldwell I, Martin D, Vitale-Cross L, Marko K, Firriolo JM, et al. Mesenchymal stromal cells from infants with simple polydactyly modulate immune responses more efficiently than adult mesenchymal stromal cells. Cytotherapy. 2019;21(2):148-161.
[10] Hsia HC, Hutti JE, Baldwin AS. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292(13):5405-5417.
[11] Al-Massri KF, Ahmed LA, El-Abhar HS. Mesenchymal stem cells therapy enhances the efficacy of pregabalin and prevents its motor impairment in paclitaxel-induced neuropathy in rats: Role of Notch1 receptor and JAK/STAT signaling pathway. Behav Brain Res. 2019;360:303-311.
[12] Mossahebi-Mohammadi M, Quan M, Zhang JS, Li X. FGF Signaling Pathway: A Key Regulator of Stem Cell Pluripotency. Front Cell Dev Biol. 2020,18;8:79.
[13] Fritsch M, Günther SD, Schwarzer R, Albert MC, Schorn F, Werthenbach JP, et al. Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. Nature. 2019;575(7784):683-687.
[14] Schwarzer R, Laurien L, Pasparakis M. New insights into the regulation of apoptosis, necroptosis, and pyroptosis by receptor interacting protein kinase 1 and caspase-8. Curr Opin Cell Biol. 2020;63:186-193.
[15] Yin F, Zhou H, Fang Y, Li C, He Y, Yu L, et al. Astragaloside IV alleviates ischemia reperfusion-induced apoptosis by inhibiting the activation of key factors in death receptor pathway and mitochondrial pathway. J Ethnopharmacol. 2020,10;248:112319.
[16] Auffret M, Cottin J, Vial T, Cucherat M. Clomiphene citrate and neural tube defects: a meta-analysis of controlled observational studies. BJOG. 2019;126(9):1127-1133.
[17] Zou J, Wang F, Yang X, Wang H, Niswander L, Zhang T, et al. Association between rare variants in specific functional pathways and human neural tube defects multiple subphenotypes. Neural Dev. 2020,10;15(1):8.
[18] Zohn IE. Mouse Models of Neural Tube Defects. Adv Exp Med Biol. 2020;1236:39-64.
[19] Zhang L, Dong Y, Wang W, Zhao T, Huang T, Khan A, et al. Ethionine Suppresses Mitochondria Autophagy and Induces Apoptosis via Activation of Reactive Oxygen Species in Neural Tube Defects. Front Neurol. 2020,7;11:242.
[20] Wei X, Cao S, Ma W, Zhang C, Gu H, Liu D, et al. Intra-Amniotic Delivery of CRMP4 siRNA Improves Mesenchymal Stem Cell Therapy in a Rat Spina Bifida Model. Mol Ther Nucleic Acids. 2020,5;20:502-517.
[21] Wu J, Bao Y, Lu X, Wu L, Zhang T, Guo J, et al. Polymorphisms in MTHFD1 Gene and Susceptibility to Neural Tube Defects: A Case-Control Study in a Chinese Han Population with Relatively Low Folate Levels. Med Sci Monit. 2015,4;21:2630-7.
[22] Li X, Yuan Z, Wei X, Li H, Zhao G, Miao J, et al. Application potential of bone marrow mesenchymal stem cell (BMSCs) based tissue-engineering for spinal cord defect repair in rat fetuses with spina bifida aperta. J Mater Sci Mater Med. 2016;27(4):77.
[23] Xue J, Gu H, Liu D, Ma W, Wei X, Zhao L, et al. Mitochondrial dysfunction is implicated in retinoic acid-induced spina bifida aperta in rat fetuses. Int J Dev Neurosci. 2018;68:39-44.
[24] Li H, Zhang Z, Gao C, Wu S, Duan Q, Wu H, et al. Combination chemotherapy of valproic acid (VPA) and gemcitabine regulates STAT3/Bmi1 pathway to differentially potentiate the motility of pancreatic cancer cells. Cell Biosci. 2019,18;9:50.
[25] Tummers B, Green DR. Caspase-8: regulating life and death. Immunol Rev. 2017;277(1):76-89.
[26] Wu Y, Wang F, Reece EA, Yang P. Curcumin ameliorates high glucose-induced neural tube defects by suppressing cellular stress and apoptosis. Am J Obstet Gynecol. 2015;212(6):802.e1-8.
[27] Wilson LJ, Myat A, Sharma A, Maden M, Wingate RJ. Retinoic acid is a potential dorsalising signal in the late embryonic chick hindbrain. BMC Dev Biol. 2007,19;7:138.
[28] Chawla B, Swain W, Williams AL, Bohnsack BL. Retinoic Acid Maintains Function of Neural Crest-Derived Ocular and Craniofacial Structures in Adult Zebrafish. Invest Ophthalmol Vis Sci. 2018,1;59(5):1924-1935.
[29] Duzyj CM, Paidas MJ, Jebailey L, Huang JS, Barnea ER. PreImplantation factor (PIF*) promotes embryotrophic and neuroprotective decidual genes: effect negated by epidermal growth factor. J Neurodev Disord. 2014;6(1):36.
[30] An JH, Li FP, He P, Chen JS, Cai ZG, Liu SR, et al. Characteristics of Mesenchymal Stem Cells Isolated from the Bone Marrow of Red Pandas. Zoology (Jena). 2020;140:125775.
[31] Mukhamedshina YO, Gracheva OA, Mukhutdinova DM, Chelyshev YA, Rizvanov AA. Mesenchymal stem cells and the neuronal microenvironment in the area of spinal cord injury. Neural Regen Res. 2019;14(2):227-237.
[32] Jin W. Role of JAK/STAT3 Signaling in the Regulation of Metastasis, the Transition of Cancer Stem Cells, and Chemoresistance of Cancer by Epithelial-Mesenchymal Transition. Cells. 2020,15;9(1):217.
[33] MuhChyi C, Juliandi B, Matsuda T, Nakashima K. Epigenetic regulation of neural stem cell fate during corticogenesis. Int J Dev Neurosci. 2013;31(6):424-33.
[34] Lee N, Neitzel KL, Devlin BK, MacLennan AJ. STAT3 phosphorylation in injured axons before sensory and motor neuron nuclei: potential role for STAT3 as a retrograde signaling transcription factor. J Comp Neurol. 2004,5;474(4):535-45.
[35] Gao S, Durstine JL, Koh HJ, Carver WE, Frizzell N, Carson JA. Acute myotube protein synthesis regulation by IL-6-related cytokines. Am J Physiol Cell Physiol. 2017,1;313(5):C487-C500.
[36] Aberg MA, Ryttsén F, Hellgren G, Lindell K, Rosengren LE, MacLennan AJ, et al. Selective introduction of antisense oligonucleotides into single adult CNS progenitor cells using electroporation demonstrates the requirement of STAT3 activation for CNTF-induced gliogenesis. Mol Cell Neurosci. 2001;17(3):426-43.
[37] Su Y, Chen Z, Du H, Liu R, Wang W, Li H, et al. Silencing miR-21 induces polarization of astrocytes to the A2 phenotype and improves the formation of synapses by targeting glypican 6 via the signal transducer and activator of transcription-3 pathway after acute ischemic spinal cord injury. FASEB J. 2019;33(10):10859-10871.
[38] Fathy M, Okabe M, M Othman E, Saad Eldien HM, Yoshida T. Preconditioning of Adipose-Derived Mesenchymal Stem-Like Cells with Eugenol Potentiates Their Migration and Proliferation In Vitro and Therapeutic Abilities in Rat Hepatic Fibrosis. Molecules. 2020,26;25(9):2020.
[39] Brick RM, Sun AX, Tuan RS. Neurotrophically Induced Mesenchymal Progenitor Cells Derived from Induced Pluripotent Stem Cells Enhance Neuritogenesis via Neurotrophin and Cytokine Production. Stem Cells Transl Med. 2018;7(1):45-58.
[40] Nicolaidou V, Wong MM, Redpath AN, Ersek A, Baban DF, Williams LM, et al. Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation. PLoS One. 2012;7(7):e39871.
[41] Cosenza M, Civallero M, Fiorcari S, Pozzi S, Marcheselli L, Bari A, et al. The histone deacetylase inhibitor romidepsin synergizes with lenalidomide and enhances tumor cell death in T-cell lymphoma cell lines. Cancer Biol Ther. 2016,2;17(10):1094-1106.
[42] Wu M, Song D, Li H, Yang Y, Ma X, Deng S, et al. Negative regulators of STAT3 signaling pathway in cancers. Cancer Manag Res. 2019,29;11:4957-4969.
[43] Nakashima K, Yanagisawa M, Arakawa H, Kimura N, Hisatsune T, Kawabata M, et al. Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science. 1999,16;284(5413):479-82.
[44] März P, Ozbek S, Fischer M, Voltz N, Otten U, Rose-John S. Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor. Eur J Biochem.2002;269(12):3023-31.
[45] Kober AM, Legewie S, Pforr C, Fricker N, Eils R, Krammer PH, et al. Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation. Cell Death Dis. 2011,6;2(10):e212.
[46] Inman GJ, Allday MJ. Apoptosis induced by TGF-beta 1 in Burkitt's lymphoma cells is caspase 8 dependent but is death receptor independent. J Immunol. 2000,1;165(5):2500-10.