1. The American Cancer Society medical and editorial content team. About Pancreatic Cancer. (2019, February 11). Retrieved July 20, 2020, from https://www.cancer.org/content/dam/CRC/PDF/Public/8778.00.pdf
2. The American Cancer Society medical and editorial content team. Survival Rates for Pancreatic Cancer. (2020, January 8). Retrieved July 20, 2020 from https://www.cancer.org/cancer/pancreatic-cancer/detection-diagnosis-staging/survival-rates.html
3. Saad AM, Turk T, Al-Husseini MJ, Abdel-Rahman O. Trends in pancreatic adenocarcinoma incidence and mortality in the United States in the last four decades; a SEER-based study. BMC Cancer (2018) 18(1):688. doi: 10.1186/s12885-018-4610-4
4. Engreitz JM, Haines JE, Perez EM, Munson G, Chen J, Kane M, et al. Local regulation of gene expression by lncRNA promoters, transcription and splicing. Nature (2016) 539 (7629):452-5. doi: 10.1038/nature20149
5. Wang JJ, Wang X, Song YX, Zhao JH, Sun JX, Shi JX, et al. Circulating Noncoding RNAs Have a Promising Future Acting as Novel Biomarkers for Colorectal Cancer. Dis Markers (2019) 2019:2587109. doi: 10.1155/2019/2587109.
6. Huang X, Zhi X, Gao Y, Ta N, Jiang H, Zheng J. LncRNAs in pancreatic cancer. Oncotarget (2016) 7(35):57379-90. doi: 10.18632/oncotarget.10545
7. Gu ZR, Liu W. The LncRNA AL161431.1 targets miR-1252-5p and facilitates cellular proliferation and migration via MAPK signaling in endometrial carcinoma. Eur Rev Med Pharmacol Sci (2020) 24(5):2294-302. doi: 10.26355/eurrev_202003_20495
8. De Troyer L, Zhao P, Pastor T, Baietti MF, Barra J, Vendramin R, et al. Stress-induced lncRNA LASTR fosters cancer cell fitness by regulating the activity of the U4/U6 recycling factor SART3. Nucleic Acids Research (2020) 48(5):2502-17. doi: 10.1093/nar/gkz1237
9. Ju Q, Zhao YJ, Ma S, Li XM, Zhang H, Zhang SQ, et al. Genome-wide analysis of prognostic-related lncRNAs, miRNAs and mRNAs forming a competing endogenous RNA network in lung squamous cell carcinoma. J Cancer Res Clin Oncol (2020) 146(7), 1711-23. doi: 10.1007/s00432-020-03224-8
10. Wang Y, Gao R, Li J, Tang S, Li S, Tong Q, Mao Y. Circular RNA hsa_circ_0003141 promotes tumorigenesis of hepatocellular carcinoma via a miR-1827/UBAP2 axis. Aging (Albany NY) (2020) 12(10):9793-806. doi: 10.18632/aging.103244
11. Wei L, Ye H, Li G, Lu Y, Zhou Q, Zheng S, et al. Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer. Cell Death Dis (2018) 9(11):1065. doi: 10.1038/s41419-018-1104-x
12. Varghese F, Bukhari AB, Malhotra R, De A. IHC Profiler: an open source plugin for the quantitative evaluation and automated scoring of immunohistochemistry images of human tissue samples. PLoS One (2014) 9(5):e96801. doi: 10.1371/journal.pone.0096801
13. Pijuan J, Barceló C, Moreno DF, Maiques O, Sisó P, Marti RM, et al. In vitro Cell Migration, Invasion, and Adhesion Assays: From Cell Imaging to Data Analysis. Front Cell Dev Biol (2019) 7:107. doi: 10.3389/fcell.2019.00107
14. Jonkman JEN, Cathcart JA, Xu F, Bartolini ME, Amon JE, Stevens KM, et al. An introduction to the wound healing assay using live-cell microscopy. Cell Adh Migr (2014) 8(5):440-51. doi: 10.4161/cam.36224
15. Genomic Data Commons Data Portal. Retrieved July 20, 2020 from https://portal.gdc.cancer.gov/projects/TCGA-PAAD
16. Bioconductor. Differential gene expression analysis based on the negative binomial distribution. Retrieved July 20, 2020 from https://bioconductor.org/packages/release/bioc/html/DESeq2.html
17. Tang Z, Li C, Kang B, Gao G, Li C, Zhang Z. GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses. Nucleic Acids Res (2017) 45(W1):W98-102. doi: 10.1093/nar/gkx247
18. The Gene Ontology Consortium. The Gene Ontology Resource: 20 years and still GOing strong. Nucleic Acids Res (2019) 47(D1):D330-D8. doi: 10.1093/nar/gky1055
19. Tahira AC, Kubrusly MS, Faria MF, Dazzani B, Fonseca RS, Maracaja-Coutinho V, et al. Long noncoding intronic RNAs are differentially expressed in primary and metastatic pancreatic cancer. Mol Cancer (2011) 10:141. doi: 10.1186/1476-4598-10-141
20. Zhou X, Gao W, Hua H, Ji Z. LncRNA-BLACAT1 Facilitates Proliferation, Migration and Aerobic Glycolysis of Pancreatic Cancer Cells by Repressing CDKN1C via EZH2-Induced H3K27me3. Front Oncol (2020) 10:539805. doi: 10.3389/fonc.2020.539805.
21. Gong R, Jiang Y. Non-coding RNAs in Pancreatic Ductal Adenocarcinoma. Front Oncol (2020) 10:309. doi: 10.3389/fonc.2020.00309.
22. Ros G, Pegoraro S, De Angelis P, Sgarra R, Zucchelli S, Gustincich S, et al. HMGA2 Antisense Long Non-coding RNAs as New Players in the Regulation of HMGA2 Expression and Pancreatic Cancer Promotion. Front Oncol (2020) 9:1526. doi: 10.3389/fonc.2019.01526.
23. Lu Y, Tang L, Zhang Z, Li S, Liang S, Ji L, et al. Long Noncoding RNA TUG1/miR-29c Axis Affects Cell Proliferation, Invasion, and Migration in Human Pancreatic Cancer. Dis Markers (2018) 2018, 6857042. doi: 10.1155/2018/6857042
24. Loh CY, Chai JY, Tang TF, Wong WF, Sethi G, Shanmugam MK, et al. The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges. Cells (2019) 8(10):1118. doi: 10.3390/cells8101118
25. Niehrs C. The complex world of WNT receptor signalling. Nat Rev Mol Cell Biol (2012) 13(12):767-79. doi: 10.1038/nrm3470
26. Chen H, Zhou X, Shi Y, Yang J. Roles of p38 MAPK and JNK in TGF-β1-induced human alveolar epithelial to mesenchymal transition. Arch Med Res (2013) 44(2):93-8. doi: 10.1016/j.arcmed.2013.01.004
27. Leader M, Collins M, Patel J, Henry K. Vimentin: an evaluation of its role as a tumour marker. Histopathology (1987) 11(1):63-72. doi: 10.1111/j.1365-2559.1987.tb02609.x
28. Fuchs E, Weber K. Intermediate filaments: structure, dynamics, function, and disease. Annu Rev Biochem (1994) 63:345-82. doi: 10.1146/annurev.bi.63.070194.002021
29. Myoteri D, Dellaportas D, Lykoudis PM, Apostolopoulos A, Marinis A, Zizi-Sermpetzoglou A. Prognostic Evaluation of Vimentin Expression in Correlation with Ki67 and CD44 in Surgically Resected Pancreatic Ductal Adenocarcinoma. Gastroenterol Res Pract (2017) 2017:9207616. doi: 10.1155/2017/9207616
30. Ma G, Li G, Gou A, Xiao Z, Xu Y, Song S, et al. Long non-coding RNA ELFN1-AS1 in the pathogenesis of pancreatic cancer. Ann Transl Med (2021) 9(10):877. doi: 10.21037/atm-21-2376