The measurement of thyroid CT value, mean iodine concentration (Figure 1a,b), thyroid volume (Figure 2a,b) and total iodine content
The CT value of 31 adult thyroid tissues was 89.37±16.14 Hu, the average iodine concentration was 1.28±0.48 mg/ml, the volume of thyroid was 13.5±4.28 ml, and the total iodine content of thyroid was 16.89±7.42 mg.
Detection of Thyroid Function Related Indicators (Table 1)
A total of 30 cases were detected for the five thyroid function index, including FT3, FT4, TSH, TT3 and TT4. In the other case, only three out five thyroid function index were collected, namely FT3, FT4 and TSH.
Correlation analysis of age, mean iodine concentration, volume and thyroid iodine content with thyroid function index (Table 2).
Correlation analysis of the results showed that age was negatively correlated with FT3, while CT value was positively correlated with FT3 (Figure 3a,b). Total iodine content of thyroid was positively correlated with FT3 (Figure3c), and negatively correlated with TSH (Figure3d). Thyroid iodine concentration was positively correlated with both FT3 and TT3 (Figure e,f).
Table 1 Descriptive analysis of thyroid function
|
FT3 (pmol/L)
|
FT4 (pmol/L)
|
TSH(μIU/ml)
|
T3(μIU/ml)
|
T4(pmol/L)
|
minimum
|
3.00
|
6.89
|
0.30
|
0.62
|
69.92
|
maximum
|
5.78
|
13.42
|
8.56
|
1.92
|
127.01
|
average
|
4.7274
|
10.4023
|
2.7223
|
1.4477
|
101.5583
|
standard deviation
|
0.69500
|
1.59359
|
1.90769
|
0.30156
|
11.75984
|
reference Range
|
3.9-7.0
|
7.64-16.03
|
0.34-5.6
|
0.34-5.6
|
69.97-152.52
|
sample size
|
31
|
31
|
31
|
30
|
30
|
Table 2 Correlation analysis between iodine level and thyroid function index Spearman
|
|
FT3
|
T3
|
FT4
|
T4
|
TSH
|
CT值
|
age
|
r Value
|
-0.393*
|
-0.114
|
-0.031
|
0.358
|
0.11
|
-0.354
|
P Value
|
0.029
|
0.549
|
0.867
|
0.052
|
0.557
|
0.051
|
volume
|
R Value
|
0.213
|
-0.032
|
-0.023
|
0.098
|
-0.318
|
-0.081
|
P Value
|
0.25
|
0.866
|
0.904
|
0.606
|
0.081
|
0.663
|
total iodine content
|
R Value
|
0.462**
|
0.281
|
0.117
|
0.161
|
-0.429*
|
0.466**
|
P Value
|
0.009
|
0.132
|
0.532
|
0.395
|
0.016
|
0.008
|
average iodine concentration
|
R Value
|
0.400*
|
0.397*
|
0.009
|
0.157
|
-0.161
|
0.669**
|
P Value
|
0.026
|
0.03
|
0.961
|
0.406
|
0.386
|
0.000
|
CT value
|
R Value
|
0.408*
|
0.112
|
0.000
|
-0.051
|
-0.276
|
|
P Value
|
0.023
|
0.556
|
0.998
|
0.787
|
0.113
|
|
Sample size
|
N
|
31
|
30
|
31
|
30
|
31
|
31
|
Figure1
Figure2
Figure 1,a,b Measurement of iodine concentration in left and right lobes of thyroid by iodine mapping.
Figure2 a, b .Measurement of the volume of left and right lobes of thyroid by depicting the area of interest.
Figure 3. a. Correlation between age and FT3.
- CT value and FT3distribution.
- Total iodine content and FT3 distribution.
- Total iodine content and TSH distribution.
- Iodine concentration and FT3 distribution.
- Iodine concentration and TT3 distribution.