Background: This study aimed to assess the effect of a 980-nm diode laser following chemomechanical root canal preparation on the severity of post-operative pain (PP) after root canal treatment (RCT).
Methods: This study included asymptomatic, single-rooted teeth with a periapical index (PAI) score of 3 or 4. All the patients received RCT, including dressing with calcium hydroxide (Ca(OH) 2 ), during two visits. The patients were randomly divided into two groups ( n : 30): a control group, in which the final irrigation was performed using 5 ml of 2.5% sodium hypochlorite (NaOCI), followed by 5 ml of 17% and ethylenediaminetetraacetic acid (EDTA) and 5 ml of distilled water, and a laser group, in which the root canals were irradiated using a 980-nm diode laser after the final irrigation at both visits. The pain levels after both visits were evaluated using a visual analogue scale (VAS) after 8 h, 24 h, 48 h and 7 d. In addition, the time intervals to medication intake were recorded. The collected data were statistically analysed using the chi-square and Mann–Whitney U test ( p <0.05).
Results: The average pain level in the control group 24 h after the first visit was significantly higher than that in the laser group ( p <0.05). The average pain level 24 h and 48 h after the second visit was significantly higher in the control group ( p <0.05). The levels of PP 24 h after the first visit were higher than those after the second visit only in the control group ( p <0.05). After the first visit, analgesic use in the control group was significantly higher after 8 h (40%) and 24 h (23%) as compared with that in the laser group ( p <0.05).
Conclusions: Root canal irradiation with a diode laser may reduce PP after RCT in single-rooted teeth with a PAI score of 3 or 4.

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On 14 Jan, 2021
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Received 27 Dec, 2020
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On 03 Oct, 2020
Received 29 Sep, 2020
Received 16 Sep, 2020
On 09 Sep, 2020
Invitations sent on 04 Sep, 2020
On 04 Sep, 2020
On 17 Aug, 2020
On 16 Aug, 2020
On 16 Aug, 2020
On 14 Jan, 2021
On 13 Jan, 2021
On 13 Jan, 2021
On 13 Jan, 2021
Received 27 Dec, 2020
Invitations sent on 08 Dec, 2020
On 08 Dec, 2020
On 01 Dec, 2020
On 01 Dec, 2020
On 01 Dec, 2020
Posted 29 Oct, 2020
On 25 Nov, 2020
Received 17 Nov, 2020
Received 14 Nov, 2020
On 28 Oct, 2020
Invitations sent on 25 Oct, 2020
On 25 Oct, 2020
On 21 Oct, 2020
On 20 Oct, 2020
On 20 Oct, 2020
On 03 Oct, 2020
Received 29 Sep, 2020
Received 16 Sep, 2020
On 09 Sep, 2020
Invitations sent on 04 Sep, 2020
On 04 Sep, 2020
On 17 Aug, 2020
On 16 Aug, 2020
On 16 Aug, 2020
Background: This study aimed to assess the effect of a 980-nm diode laser following chemomechanical root canal preparation on the severity of post-operative pain (PP) after root canal treatment (RCT).
Methods: This study included asymptomatic, single-rooted teeth with a periapical index (PAI) score of 3 or 4. All the patients received RCT, including dressing with calcium hydroxide (Ca(OH) 2 ), during two visits. The patients were randomly divided into two groups ( n : 30): a control group, in which the final irrigation was performed using 5 ml of 2.5% sodium hypochlorite (NaOCI), followed by 5 ml of 17% and ethylenediaminetetraacetic acid (EDTA) and 5 ml of distilled water, and a laser group, in which the root canals were irradiated using a 980-nm diode laser after the final irrigation at both visits. The pain levels after both visits were evaluated using a visual analogue scale (VAS) after 8 h, 24 h, 48 h and 7 d. In addition, the time intervals to medication intake were recorded. The collected data were statistically analysed using the chi-square and Mann–Whitney U test ( p <0.05).
Results: The average pain level in the control group 24 h after the first visit was significantly higher than that in the laser group ( p <0.05). The average pain level 24 h and 48 h after the second visit was significantly higher in the control group ( p <0.05). The levels of PP 24 h after the first visit were higher than those after the second visit only in the control group ( p <0.05). After the first visit, analgesic use in the control group was significantly higher after 8 h (40%) and 24 h (23%) as compared with that in the laser group ( p <0.05).
Conclusions: Root canal irradiation with a diode laser may reduce PP after RCT in single-rooted teeth with a PAI score of 3 or 4.

Figure 1
This is a list of supplementary files associated with this preprint. Click to download.
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