Abdel-Monem, O.A., El-Baz, A.F., Shetaia, Y.M., El-Sabbagh, S.M. (2012). Production and application of thermostable cellulase-free xylanase by aspergillus fumigatus from agricultural wastes Industrial Biotechnology, 8:152–161
Alfafara, C. G., Kanda, A., Shioi, T., Shimizu, H., Shioya, S., Suga, K. I. 1992a. Effect of amino acids on glutathione production by Saccharomyces cerevisiae. Applied Microbiology and Biotechnology, 36, 538-540.
Alfafara, C., Miura, K., Shimizu, H., Shioya, S., Suga, K. I. 1992b. Cysteine addition strategy for maximum glutathione production in fed-batch culture of Saccharomyces cerevisiae. Applied Microbiology and Biotechnology, 37, 141-146.
Bachhawat, A.K., Ganguli, D., Kaur, J., Kasturia, N., Thakur, A., Kaur, H., Kumar, A. Yadav, A. 2009. Glutathione Production in Yeast, in: T. Satyanarayana, G. Kunze (Eds.), Springer, Dordrecht, Netherlands, pp. 259-280.
Bai, M., Zhou, J-M., Perrett, S. (2004). The Yeast Prion Protein Ure2 Shows Glutathione Peroxidase Activity in Both Native and Fibrillar Forms. The Journal of Biological Chemistry. 279:50025-50030.
Ballatori, N., Krance, S. M., Notenboom, S., Shi, S., Tieu, K., Hammond, C. L. 2009. Glutathione dysregulation and the etiology and progression of human diseases. Biological Chemistry, 390(3), 191-214.
Bradford, M.M. (1976) A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding. Analytical Biochem. 72, 248-254.
Brigelius-Flohé R, Maiorino M. (2013). Glutathione peroxidases. Biochim Biophys Acta. 1830:3289-303.
Buts, J.P. 1999. Mechanisms of action of biotherapeutic agents. In Biotherapeutic agents and infectious diseases: 27-46. Humana Press.
Cha, J. Y., Park, J. C., Jeon, B. S., Lee, Y. C., Cho, Y. S. 2004. Optimal fermentation conditions for enhanced glutathione production by Saccharomyces cerevisiae FF-8. Journal of Microbiology -Seoul, 42 (1), 51-55.
Cui, X., Wan, J., Zhang, X., Wu, H., Li, Z., Ye, Q. 2019. Efficient glutathione production in metabolically engineered Escherichia coli strains using constitutive promoters. Journal of Biotechnology, 289, 39-45.
Dan, L.I.U., Yiman, Q.I., Ning, Z.H. A.O., Youfang, C.A.O., Junnan, X.U., Mingtao, F.A.N. 2020. Multivariate analysis reveals effect of glutathione-enriched inactive dry yeast on amino acids and volatile components of kiwi wine. Food Chemistry, 127086.
Du, L. P., Hao, R. X., Xiao, D. G., Guo, L. L., Gai, W. D. 2012. Research on the Characteristics and Culture Conditions of Saccharomyces boulardii. In: Advanced materials research, Vol. 343, pp. 594-598. Trans Tech Publications Ltd.
Edwards-Ingram, L., Gitsham, P., Burton, N., Warhurst, G., Clarke, I., Hoyle, D., Stateva, L. 2007. Genotypic and physiological characterization of Saccharomyces boulardii, the probiotic strain of Saccharomyces cerevisiae. Appl. Environ. Microbiol., 73(8), 2458-2467.
El Baz, A.F., Shetaia, Y.M., Elkhouli R.R. 2011. Xylitol production by Candida tropicalis under different statistically optimized growth conditions. African Journal of Biotechnology, 10(68), 15353 -15363.
El Baz, A.F., Sorour, N.M., Shetaia, Y.M. 2016. Trichosporon jirovecii–mediated synthesis of cadmium sulfide nanoparticles. Journal of Basic Microbiology, 56(5), 520–530.
El Baz, A.F., El-Enshasy, H.A., Shetaia, Y.M., Mahrous, H., Othman, N.Z., Yousef, A.E. 2018. Semi-industrial Scale Production of a New Yeast with Probiotic Traits, Cryptococcus sp. YMHS, Isolated from the Red Sea. Probiotics and Antimicrobial Proteins 10 (1), 77-88.
El Baz, F.N., Gamal, R.F., ElBaz, A.F., Ibrahim, N.E., ElMekawy, A. (2017) Biochemical and biotechnological studies on a novel purified bacillus cholesterol oxidase tolerant to solvent and thermal stress. Biocatalysis and Biotransformation, 35: 205–214
El Baz, A.F., Shetaia, Y.M., Elkhouli, R.R. (2011) Kinetic behavior of Candida tropicalis during xylitol production using semi-synthetic and hydrolysate based media. African Journal of Biotechnology, 10: 16617–16625.
El Mekawy, A., Hegab, H.M., El-Baz, A., Hudson, S.M. (2013).Kinetic properties and role of bacterial chitin deacetylase in the bioconversion of chitin to chitosan. Recent Patents on Biotechnology, 7: 234–241.
El-Sayed, A.S.A., Abdel-Azim, S., Ibrahim H., Yassin, M.A., Abdel-Ghany S., Esener, S. Ali, GS (2015): Biochemical stability and molecular dynamic characterization of Aspergillus fumigatus cystathionine g-Lyase in response to various reaction effectors. Enzyme and Microbial Technology 81: 31–46.
El-Sayed, A.S.A., Hassan, A.E.A., Shindia, A.A., Mohamed, S.G., Sitohy, M.Z. (2016) Aspergillus flavipes L-methionine γ-lyase dextran conjugates with enhanced structural proteolytic stability and anticancer efficiency. Journal of Molecular Catalysis: B-enzymatic, 133: S15-S24.
El-Sayed, A.S.A., Shindia, A.A., Abou-Zaid, A.A. Yassin, A.M. (2019): Aspergillus nidulans arginine deiminase- Dextran conjugates with enhanced molecular stability, proteolytic resistance, pharmacokinetic properties and anticancer activity. Enzyme and Microbial Technology 131: 12: 109432
Fietto, J. L., Araújo, R. S., Valadão, F. N., Fietto, L. G., Brandão, R. L., Neves, M., Castro, I. M. 2004. Molecular and physiological comparisons between Saccharomyces cerevisiae and Saccharomyces boulardii. Canadian Journal of Microbiology, 50(8), 615-621.
Gushima, H., Yasuda, S., Soeda, E., Yokota, M., Kondo, M., Kimura, A. 1984. Complete nucleotide sequence of the E. coli glutathione synthetase gsh-II. Nucleic Acids Research, 12(24), 9299-9307.
Habenicht, A., Hille, S., Knöchel, W. 1993. Molecular cloning of the large subunit of glutathione synthetase from Xenopus laevis embryos. Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression, 1174(3), 295-298.
Hassan, A., Sorour, N.M., El Baz, A.F., Shetaia, Y.M. 2019. Simple synthesis of bacterial cellulose/ magnetite nanoparticles composite for the removal of antimony from aqueous solution. International Journal of Environmental Science and Technology 16 (3), 1433-1448.
Hong, J. Y., Son, S. H., Hong, S. P., Yi, S. H., Kang, S. H., Lee, N. K., Paik, H. D. 2019. Production of β-glucan, glutathione, and glutathione derivatives by probiotic Saccharomyces cerevisiae isolated from cucumber jangajji. LWT, 100, 114-118.
Huang, C.S., He, W., Meister, A., Anderson, M.E. 1995. Amino acid sequence of rat kidney glutathione synthetase. Proceedings of the National Academy of Sciences, 92(4), 1232-1236.
Johnston, R.B., Bloch, K. 1951. Enzymatic synthesis of glutathione. J. Biol. Chem., 188, 221-240.
Khullar, S., Reddy, M.S. 2020. Arsenic toxicity and its mitigation in ectomycorrhizal fungus Hebeloma cylindrosporum through glutathione biosynthesis. Chemosphere, 240, 124914.
Laemmli, U. (1970) Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4. Nature 227, 680–685.
Lei, Z., Chen, H., Huang, D., Zhai, Y., Shu, G. 2016. Optimization of Medium Compositions for Saccharomyces Boulardii by Box-Behnken Design. Scientific Study & Research. Chemistry & Chemical Engineering, Biotechnology, Food Industry, 17(4), 405.
Li, C., Xia, J.Y., Chu, J., Wang, Y.H., Zhuang, Y.P., Zhang, S.L. 2013. CFD analysis of the turbulent flow in baffled shake flasks. Biochemical Engineering Journal, 70, 140-150.
Li C, Deng X, Zhang W, Xie X, Conrad M, Liu Y, Angeli JPF, Lai L. (2019) Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4. J Med Chem. 2019 Jan 10; 62(1):266-275.
Li, Y., Wei, G., Chen, J. 2004. Glutathione: a review on biotechnological production. Applied Microbiology and Biotechnology, 66:233-242.
Li, S., Yan, T., Yang, J-Q., Oberley, T.D., Oberley. L.W. (2000) The Role of Cellular Glutathione Peroxidase Redox Regulation in the Suppression of Tumor Cell Growth by Manganese Superoxide Dismutase. Cancer Res 60, 3927-3939.
Liang, G.B., Du, G.C., Chen, J. 2008. A novel strategy of enhanced glutathione production in high cell density cultivation of Candida utilis-cysteine addition combined with dissolved oxygen controlling. Enzyme and Microbial Technology, 42(3), 284-289.
Liang, G., Liao, X., Du, G., Chen, J. 2009. A new strategy to enhance glutathione production by multiple H2O2-induced oxidative stresses in Candida utilis. Bioresource Technology, 100, 350-355.
Liang, G., Mo, Y., Du, G. 2010. Optimization of sodium dedecyl sulfate (SDS) addition coupled with adenosine triphosphate (ATP) regeneration for glutathione overproduction in high density cultivation of Candida utilis. Enzyme and Microbial Technology, 46, 526-533.
Lienkamp, A.C., Heine, T., Tischler, D. 2020. Glutathione: a powerful but rare cofactor among actinobacteria. In: Advances in Applied Microbiology, Academic Press. Vol. 110, pp. 181-217.
Lorenz, E., Schmacht, M., Senz, M. 2016. Evaluation of cysteine ethyl ester as efficient inducer for glutathione overproduction in Saccharomyces spp. Enzyme and microbial technology, 93, 122-131.
Lorenz, E., Schmacht, M., Stahl, U., Senz, M. 2015. Enhanced incorporation yield of cysteine for glutathione overproduction by fed-batch fermentation of Saccharomyces cerevisiae. Journal of Biotechnology, 216, 131-139.
McFarland, L.V., Bernasconi, P. 1993. Saccharomyces boulardii'. A review of an innovative biotherapeutic agent. Microbial Ecology in Health and Disease, 6(4), 157-171.
Meister, A. Anderson, M.E. 1983. Glutathione. Annual review of biochemistry, 52(1), 711-760.
Mezzetti A, Di Ilio C, Calafiore AM, Aceto A, Marzio L, Frederici G, Cuccurullo F. Glutathione peroxidase, glutathione reductase and glutathione transferase activities in the human artery, vein and heart. J Mol Cell Cardiol. 1990 Sep;22(9):935-8.
Mitterdorfer, G., Mayer, H.K., Kneifel, W., Viernstein, H. 2002. Clustering of Saccharomyces boulardii strains within the species S. cerevisiae using molecular typing techniques. Journal of Applied Microbiology, 93(4), 521-530.
Mutoh, N., Nakagawa, C.W., Hayashi, Y. 1995. Molecular cloning and nucleotide sequencing of the γ-glutamylcysteine synthetase gene of the fission yeast Schizosaccharomyces pombe. The Journal of Biochemistry, 117(2), 283-288.
Mutoh, N., Nakagawa, C.W., Ando, S., Tanabe, K., Hayashi, Y. 1991. Cloning and sequencing of the gene encoding the large subunit of glutathione synthetase of Schizosaccharomyces pombe. Biochemical and Biophysical Research Communications, 181(1), 430-436.
Myers, R.H., Montgomery, D.C., Anderson-Cook, C.M. 2016. Response surface methodology: process and product optimization using designed experiments. John Wiley & Sons.
NCBI Resource Coordinators, 2014. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res. doi:10.1093/nar/gkv1 290.
Ohtake, Y., Watanabe, K., Tezuka, H., Ogata, T., Yabuuchi, S., Murata, K., Kimura, A. 1989. Expression of the glutathione synthetase gene of Escherichia coli B in Saccharomyces cerevisiae. Journal of Fermentation and Bioengineering, 68(6), 390-394.
Penninckx, M.J. 2002. An overview on glutathione in Saccharomyces versus non-conventional yeasts. FEMS yeast research 2(3), 295-305.
Perricone, N.V. 2011. "Topical Acyl Glutathione Formulations." U.S. Patent Application 12/647,629.
Plackett, R.L, Burman, J.P. 1946. The design of optimum multifactorial experiments. Biometrika 33(4):305-325
Prima, A., Hara, K. Y., Djohan, A. C., Kashiwagi, N., Kahar, P., Ishii, J., Ogino, C. 2017. Glutathione production from mannan-based bioresource by mannanase/mannosidase expressing Saccharomyces cerevisiae. Bioresource Technology, 245, 1400-1406.
Rahman I, Kode A, Biswas SK. Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nat Protoc. 2006;1(6):3159-65.
Sabeh F, Wright T, Norton S, J: Purification and Characterization of a Glutathione Peroxidase from the Aloe vera Plant. Enzyme Protein 1993; 47:92-98.
Saing, T., Lagman, M., Castrillon, J., Gutierrez, E., Guilford, F. T., Venketaraman, V. 2016. Analysis of glutathione levels in the brain tissue samples from HIV-1-positive individuals and subject with Alzheimer's disease and its implication in the pathophysiology of the disease process. BBA clinical, 6, 38-44.
Santos, L. O., Gonzales, T. A., Ubeda, B. T., Alegre, R.M 2007. Influence of culture conditions on glutathione production by Saccharomyces cerevisiae, Appl. Microbiol. Biotechnol., 77, 763-769.
Schmacht, M., Lorenz, E., Stahl, U., Senz, M. 2017. Medium optimization based on yeast's elemental composition for glutathione production in Saccharomyces cerevisiae. Journal of Bioscience and Bioengineering, 123(5), 555-561.
Shi, C., Wang, X., Xiao, Z., Wang, R., Qiao, Y., Kan, G. 2020. Cloning, characterization and expression analysis of glutathione S-transferase from the Antarctic yeast Rhodotorula mucilaginosa AN5. Protein Expression and Purification, 167, 105518.
Tietze, F. (1969). Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues. Analytical Biochemistry. 27:502-522.
Udeh, K. O., Achremowicz, B. 1997. High-glutathione containing yeast Saccharomyces cerevisiae: optimization of production. Acta Microbiologica Polonica, 46(1), 105-114.
Wang, C., Zhang, J., Wu, H., Li, Z., Ye, Q. 2015. Heterologous gshF gene expression in various vector systems in Escherichia coli for enhanced glutathione production. Journal of Biotechnology, 214, 63-68.
Wang, D., Wang, C., Wu, H., Li, Z., Ye, Q. 2016. Glutathione production by recombinant Escherichia coli expressing bifunctional glutathione synthetase. Journal of Industrial Microbiology & Biotechnology, 43(1), 45-53.
Wang, Y., Wang, D., Wei, G., Shao, N. 2012. Enhanced co-production of S-adenosylmethionine and glutathione by an ATP-oriented amino acid addition strategy. Bioresource Technology, 107, 19-24.
Wang, Z., Tan, T., Song, J. 2007. Effect of amino acids addition and feedback control strategies on the high-cell-density cultivation of Saccharomyces cerevisiae for glutathione production. Process Biochemistry, 42(1), 108-111.
Wang, Y., Wu, S., Liu, C., Lu, X., Chen, Z. 2018. Herba Gelsemii elegantis is detoxified by ramulus et folium Mussaendae pubescentis extract by modulating hepatic cytochrome P450 and glutathione S‑transferase enzymes in rats. Experimental and Therapeutic Medicine, 15(1), 226-234.
Wei, G., Li, Y., Du, G., Chen, J. 2003. Effect of surfactants on extracellular accumulation of glutathione by Saccharomyces cerevisiae. Process Biochemistry, 38(8), 1133-1138.
Wen, S., Zhang, T., Tan, T. 2004. Utilization of amino acids to enhance glutathione production in Saccharomyces cerevisiae. Enzyme and Microbial Technology, 35(6-7), 501-507.
Wen, S., Zhang, T., Tan, T. 2005. Optimization of the amino acid composition in glutathione fermentation. Process Biochemistry, 40(11), 3474-3479.
Wu, G., Fang, Y. Z., Yang, S., Lupton, J. R., Turner, N. D. 2004. Glutathione metabolism and its implications for health. The Journal of nutrition, 134(3), 489-492.
Xiong, Z. Q., Guo, M. J., Guo, Y. X., Chu, J., Zhuang, Y. P., Zhang, S. L. 2009. Efficient extraction of intracellular reduced glutathione from fermentation broth of Saccharomyces cerevisiae by ethanol. Bioresource Technology, 100(2), 1011-1014.
Yoshida, H., Hara, K. Y., Kiriyama, K., Nakayama, H., Okazaki, F., Matsuda, F., Kondo, A. 2011. Enzymatic glutathione production using metabolically engineered Saccharomyces cerevisiae as a whole-cell biocatalyst. Applied microbiology and Biotechnology, 91(4), 1001-1006.
Zhang, J., Quan, C., Wang, C., Wu, H., Li, Z., Ye, Q. 2016. Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production. Microbial Cell Factories, 15(1), 38.
Zhang, T., Wen, S., Tan, T. 2007. Optimization of the medium for glutathione production in Saccharomyces cerevisiae. Process Biochemistry, 42(3), 454-458.
Zhang, Z., Schwartz, S., Wagner, L., Miller, W. 2000. A greedy algorithm for aligning DNA sequences. Journal of Computational Biology, 7(1-2), 203-214.