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Research
Association Between Betel Nut and Presence of Diverticulum: A Cross-Sectional Study
Wei-liang chen
Tri-Service General Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0003-0784-230X
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Current studies reporting multiple systemic effect of betel nut (BN) chewing have little analysis on colonic system. The aim of our study was to analyze the association between BN chewing and diverticulosis.
Method: This cross-sectional study is conducted from 2010 to 2016 at a medical center in Taiwan. 5586 eligible participants were enrolled in our study (all of them underwent colonoscopy, and 349 with diverticulosis). The BN chewing behavior was recorded from assessment of personal history. The diverticulosis was categorized by the presence or not according to the colonoscopies done by trained physicians from health examinations in Tri-Service General Hospital. A logistic regression model with adjusted models, with covariates from Directed Acyclic Graph, was used to determine the association between BN chewing and diverticulosis. We also analyzed the association between different exposures, including cigarette, alcohol, and BN, and diverticulosis.
Results: Our study included 3161 males and 2425 females with significantly higher prevalence rates of BN chewing behavior among males than females (11.1% versus 0.3%). In men group, BN chewing had adjusted odd ratio: 1.65(95% CI:1.12-2.44) on the presence of diverticulosis. Among the combination of exposures of cigarette, alcohol and BN, only the group exposed to all showed significant association between diverticulosis with adjusted OR: 1.909(95% CI: 1.188-3.065). Further subgroup analysis displayed adjusted OR: 2.310(95% CI:1.245-4.287) in obesity Taiwanese male.
Conclusion: BN chewing is independently associated with diverticulosis in Taiwanese male.
Keywords
Betel nut, Diverticulosis
Figure 1
Due to technical limitations, table 1 is only available as a download in the Supplemental Files section.
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This is a preprint. It has not completed peer review.
Research
Association Between Betel Nut and Presence of Diverticulum: A Cross-Sectional Study
Wei-liang chen
Tri-Service General Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0003-0784-230X
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 18 Aug, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Environmental Policy
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Current studies reporting multiple systemic effect of betel nut (BN) chewing have little analysis on colonic system. The aim of our study was to analyze the association between BN chewing and diverticulosis.
Method: This cross-sectional study is conducted from 2010 to 2016 at a medical center in Taiwan. 5586 eligible participants were enrolled in our study (all of them underwent colonoscopy, and 349 with diverticulosis). The BN chewing behavior was recorded from assessment of personal history. The diverticulosis was categorized by the presence or not according to the colonoscopies done by trained physicians from health examinations in Tri-Service General Hospital. A logistic regression model with adjusted models, with covariates from Directed Acyclic Graph, was used to determine the association between BN chewing and diverticulosis. We also analyzed the association between different exposures, including cigarette, alcohol, and BN, and diverticulosis.
Results: Our study included 3161 males and 2425 females with significantly higher prevalence rates of BN chewing behavior among males than females (11.1% versus 0.3%). In men group, BN chewing had adjusted odd ratio: 1.65(95% CI:1.12-2.44) on the presence of diverticulosis. Among the combination of exposures of cigarette, alcohol and BN, only the group exposed to all showed significant association between diverticulosis with adjusted OR: 1.909(95% CI: 1.188-3.065). Further subgroup analysis displayed adjusted OR: 2.310(95% CI:1.245-4.287) in obesity Taiwanese male.
Conclusion: BN chewing is independently associated with diverticulosis in Taiwanese male.
Figure 1
Due to technical limitations, table 1 is only available as a download in the Supplemental Files section.