The neodymium doping of titanium dioxide with content of Nd varying from 0.01 to 0.8% was conducted by the sol-gel hydrothermic method. TiO2/Nd is then coated on rice husk ash to produce modified TiO2/Nd/rice husk ash material using Nd content of 0.36% w/w. The materials’ structure characteristic and photocatalytic properties have been analyzed by the XRD, EDX, TEM, SEM, forbidden zone energy (Eg) and specific surface area (BET). TiO2/Nd material shows a higher photocatalytic decomposition capacity in comparison to TiO2 and depended on the Nd content. The Rifampicin removal efficiency of TiO2/Nd materials with Nd contents ranged from 0.36 to 0.80% had an increase of about 40% higher than that of TiO2/Nd containing Nd from 0.01 to 0.28%. This new photocatalytic TiO2/Nd/rice husk ash material is used to decompose Rifampicin. Within 90 minutes under sunlight, the Rifampicin decomposed efficiency of TiO2/Nd and TiO2/Nd/rice husk ash material reached about 86 and 75%, respectively. Even lower efficiency was obtained, the latter material was chosen for Rifampicin residue decomposition in the water under sunlight through photocatalytic process because it has some advantages such as smaller amount was needed and easily to be recovered. Rifampicin removal process, k values were found matching more to zero and first order kinetics. Especially, for powder TiO2/Nd and TiO2/Nd/Rice husk ash under solar irradiation the R2 reached about 0.98.