See the published version of this preprint at BMC Ophthalmology.
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Research article
Jibo Zhou
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Corresponding Author
ORCiD: https://orcid.org/0000-0003-0684-0302
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The current study compared optical quality before and after implantation of a posterior chamber phakic intraocular lens with a central hole V4c implantable collamer lens (ICL) under bright and dark lighting conditions by means of the Optical Quality Analysis System™ (OQAS; Visiometrics, Terrassa, Spain). Methods: This prospective study involved 91 eyes of 46 consecutive high myopia patients (15 males and 31 females, average spherical equivalent -10.50±0.33D) undergoing implantation of a V4c ICL. The modulation transfer function (MTF) cutoff frequency, Strehl ratio, objective scattering index (OSI), and predicted visual acuities (PVAs; 100%, 20%, and 9%), under different lighting conditions, were measured before and 1 week, 1 month, and 3 months after surgery. Results: All optical parameters showed significant improvements, at all time points, under dark condition after surgery. We observed no significant changes in PVA 9% at 1 week (mean value 0.539, P=0.12) or 1 month after surgery (mean value 0.573, P=0.08) under bright condition; but all other postoperative parameters improved significantly. Comparing the two lighting conditions, the OSI decreased more under dark conditions at 1 week (P=0.02), 1 month (P=0.004), and 3 months (P=0.002), but there was no significant difference in any other parameter. In addition, patients were divided into super high myopia (group S, spherical equivalent greater than -10 D) and high myopia (group H, spherical equivalent from -6 D to -10 D), the group S improved significantly more than group H in all parameters, under both bright and dark conditions. Conclusions: V4c ICL implantation improved optical quality under both bright and dark lighting conditions, and had a better ability to reduce the extent of scattering in the dark. Furthermore, group S achieved greater improvement in visual quality, which should be considered by physicians before surgery.
Keywords
Implantable collamer lens with a central hole, optical quality, OQAS, lighting condition.
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CURRENT STATUS: Published
View the published article at BMC Ophthalmology.
Version 3
Posted 02 Jan, 2020
No community comments so far
Editorial decision: Accept
On 12 Feb, 2020
Review #1 received
Received 07 Feb, 2020
Reviewer #1 agreed
On 31 Jan, 2020
Reviewers invited
Invitations sent on 31 Jan, 2020
Editor assigned
On 27 Dec, 2019
Submission checks complete
On 26 Dec, 2019
Editor invited
On 26 Dec, 2019
No comments provided
Editorial decision: Major revision
On 06 Dec, 2019
Review #2 received
Received 03 Dec, 2019
Reviewer #2 agreed
On 14 Nov, 2019
Review #1 received
Received 24 Oct, 2019
Reviewers invited
Invitations sent on 23 Oct, 2019
Reviewer #1 agreed
On 23 Oct, 2019
Editor assigned
On 23 Jul, 2019
Submission checks complete
On 22 Jul, 2019
Editor invited
On 22 Jul, 2019
No comments provided
Editorial decision: Minor revision
On 21 Jun, 2019
Review #2 received
Received 20 Jun, 2019
Reviewer #2 agreed
On 03 Jun, 2019
Reviewer #1 agreed
On 04 May, 2019
Review #1 received
Received 04 May, 2019
Submission checks complete
On 20 Apr, 2019
Editor assigned
On 20 Apr, 2019
Reviewers invited
Invitations sent on 20 Apr, 2019
Editor invited
On 10 Apr, 2019
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See the published version of this preprint at BMC Ophthalmology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Jibo Zhou
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Corresponding Author
ORCiD: https://orcid.org/0000-0003-0684-0302
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Ophthalmology.
Version 3
Posted 02 Jan, 2020
No community comments so far
Editorial decision: Accept
On 12 Feb, 2020
Review #1 received
Received 07 Feb, 2020
Reviewer #1 agreed
On 31 Jan, 2020
Reviewers invited
Invitations sent on 31 Jan, 2020
Editor assigned
On 27 Dec, 2019
Submission checks complete
On 26 Dec, 2019
Editor invited
On 26 Dec, 2019
No comments provided
Editorial decision: Major revision
On 06 Dec, 2019
Review #2 received
Received 03 Dec, 2019
Reviewer #2 agreed
On 14 Nov, 2019
Review #1 received
Received 24 Oct, 2019
Reviewers invited
Invitations sent on 23 Oct, 2019
Reviewer #1 agreed
On 23 Oct, 2019
Editor assigned
On 23 Jul, 2019
Submission checks complete
On 22 Jul, 2019
Editor invited
On 22 Jul, 2019
No comments provided
Editorial decision: Minor revision
On 21 Jun, 2019
Review #2 received
Received 20 Jun, 2019
Reviewer #2 agreed
On 03 Jun, 2019
Reviewer #1 agreed
On 04 May, 2019
Review #1 received
Received 04 May, 2019
Submission checks complete
On 20 Apr, 2019
Editor assigned
On 20 Apr, 2019
Reviewers invited
Invitations sent on 20 Apr, 2019
Editor invited
On 10 Apr, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Internal Medicine Specialties
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Ophthalmology.
Background: The current study compared optical quality before and after implantation of a posterior chamber phakic intraocular lens with a central hole V4c implantable collamer lens (ICL) under bright and dark lighting conditions by means of the Optical Quality Analysis System™ (OQAS; Visiometrics, Terrassa, Spain). Methods: This prospective study involved 91 eyes of 46 consecutive high myopia patients (15 males and 31 females, average spherical equivalent -10.50±0.33D) undergoing implantation of a V4c ICL. The modulation transfer function (MTF) cutoff frequency, Strehl ratio, objective scattering index (OSI), and predicted visual acuities (PVAs; 100%, 20%, and 9%), under different lighting conditions, were measured before and 1 week, 1 month, and 3 months after surgery. Results: All optical parameters showed significant improvements, at all time points, under dark condition after surgery. We observed no significant changes in PVA 9% at 1 week (mean value 0.539, P=0.12) or 1 month after surgery (mean value 0.573, P=0.08) under bright condition; but all other postoperative parameters improved significantly. Comparing the two lighting conditions, the OSI decreased more under dark conditions at 1 week (P=0.02), 1 month (P=0.004), and 3 months (P=0.002), but there was no significant difference in any other parameter. In addition, patients were divided into super high myopia (group S, spherical equivalent greater than -10 D) and high myopia (group H, spherical equivalent from -6 D to -10 D), the group S improved significantly more than group H in all parameters, under both bright and dark conditions. Conclusions: V4c ICL implantation improved optical quality under both bright and dark lighting conditions, and had a better ability to reduce the extent of scattering in the dark. Furthermore, group S achieved greater improvement in visual quality, which should be considered by physicians before surgery.
Figure 1
This is a list of supplementary files associated with this preprint. Click to download.
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