[1] World Health Organization. Global hepatitis report 2017 (WHO, 2017).
[2] Wang F, Fan J, Zhang Z, Gao B, Wang H. The global burden of liver disease: The major impact of China. Hepatology 2014; 60 (6): 2099-2108. doi: 10.1002/hep.27406.
[3] Liang X, Bi S, Yang W, Wang L, Cui G, Cui F, et al. Epidemiological serosurvey of Hepatitis B in China-Declining HBV prevalence due to Hepatitis B vaccination. Vaccine 2009; 27 (47): 6550-6557. doi: 10.1016/j.vaccine.2009.08.048.
[4] Liang X, Bi S, Yang W, Wang L, Cui G, Cui F, et al. Evaluation of the Impact of Hepatitis B Vaccination among Children Born during 1992–2005 in China. The Journal of Infectious Diseases 2009; 200 (1): 39-47. doi: 10.1086/599332.
[5] Tseng TC, Kao JH, Chen DS. Peginterferon alpha in the treatment of chronic hepatitis B. Expert Opin Biol Ther 2014; 14 (7): 995-1006. doi: 10.1517/14712598.2014.907784.
[6] Xiao DY, Liu ZY, Wang H. Research progress on anti-hepatitis B virus mechanisms of traditional Chinese medicine. Guizhou Medical Journal 2018; 42(02): 164-66. Doi: 10.3969/j.issn.1000-744X.2018.02.014. [in Chinese]
[7] Jin YL. Comparative study on the efficacy of Sheng-Ma-Ge-Gen-Tang and Western Medicine on measles. International Journal of Traditional Chinese Medicine 1995; (03):31. [in Chinese]
[8] Wang K, Chang J, Chiang L, Lin C. Sheng-Ma-Ge-Gen-Tang (Shoma-kakkon-to) inhibited cytopathic effect of human respiratory syncytial virus in cell lines of human respiratory tract. Journal of Ethnopharmacology 2011; 135 (2): 538-544. doi: 10.1016/j.jep.2011.03.058.
[9] Zhu YB. Treatment of 300 cases of hepatitis B with Shengma Gegen Decoction. Clinical Journal of Traditional Chinese Medicine, 1997;(05):252. [in Chinese]
[10] Li DZ, An DM, Wang KZ, Pu CZ. Clinical study on Shengma Gegen Decoction in the treatment of chronic hepatitis B during immune clearance. Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases, 2015; 25(02): 90-91. doi: 10.3969/j.issn.1005-0264.2015.02.009. [in Chinese]
[11] Ru J, Li P, Wang J, Zhou W, Li B, Huang C, et al. TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. Journal of Cheminformatics 2014; 6 (1): 13-13. doi: 10.1186/1758-2946-6-13.
[12] Jiang Y, Liu N, Zhu S, Hu X, Chang DH, Liu J. Elucidation of the Mechanisms and Molecular Targets of Yiqi Shexue Formula for Treatment of Primary Immune Thrombocytopenia Based on Network Pharmacology. Frontiers in Pharmacology 2019; 10 1136. doi: 10.3389/fphar.2019.01136.
[13] Kinjo J, Tsuchihashi R, Morito K, Hirose T, Aomori T, Nagao T, et al. Interactions of phytoestrogens with estrogen receptors α and β (III). Estrogenic activities of soy isoflavone aglycones and their metabolites isolated from human urine. Biological & Pharmaceutical Bulletin 2004; 27 (2): 185-188. doi: 10.1248/bpb.27.185.
[14] Ge L, Wan H, Tang S, Chen H, Li J, Zhang K, et al. Novel caffeoylquinic acid derivatives from Lonicera japonica Thunb. flower buds exert pronounced anti-HBV activities. RSC Advances 2018; 8 (62): 35374-35385. doi: 10.1039/C8RA07549B.
[15] Mun L, Jun MS, Kim Y, Lee YS, Kim HJ, Seo HG, et al. 7,8-didehydrocimigenol from Cimicifugae rhizoma inhibits TNF-α-induced VCAM-1 but not ICAM-1expression through upregulation of PPAR-γ in human endothelial cells. Food and Chemical Toxicology 2011; 49 (1): 166-172. doi: 10.1016/j.fct.2010.10.012.
[16] Lin TJ, Wang KC, Lin CC, Chiang LC, Chang JS. Anti-viral activity of water extract of Paeonia lactiflora pallas against human respiratory syncytial virus in human respiratory tract cell lines. Am J Chin Med 2013; 41 (3): 585-599. doi: 10.1142/S0192415X13500419.
[17] Chang JS, Wang KC, Chiang LC. Sheng-Ma-Ge-Gen-Tang inhibited Enterovirus 71 infection in human foreskin fibroblast cell line. J Ethnopharmacol 2008; 119 (1): 104-108. doi: 10.1016/j.jep.2008.06.004.
[18] Lampertico P, Agarwal K, Berg T, Buti M, Janssen HLA, Papatheodoridis GV, et al. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. Journal of Hepatology 2017; 67 (2): 370-398. doi: 10.1016/j.jhep.2017.03.021.
[19] Trépo C, Chan HLY, Lok A. Hepatitis B virus infection. Lancet 2014; 384 (9959): 2053-2063. doi: 10.1016/S0140-6736(14)60220-8.
[20] Terrault NA, Bzowej N, Chang K, Hwang JP, Jonas MM, Murad MH. AASLD guidelines for treatment of chronic hepatitis B. Hepatology 2016; 63 (1): 261-283. doi: 10.1002/hep.28156.
[21] Sarin SK, Kumar M, Lau GKK, Abbas Z, Chan HL, Chen C, et al. Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update. Hepatology International 2016; 10 (1): 1-98. doi: 10.1007/s12072-015-9675-4.
[22] Wu PT. Cimicifuga for elevation of ALT and AST in chronic hepatitis. Journal of Traditional Chinese Medicine, 2006;(04): 256-57. doi: 10.3321/j.issn:1001-1668.2006.04.007. [in Chinese]
[23] Shi WL. Cimicifuga in the treatment of drug-induced hepatitis. Journal of Traditional Chinese Medicine, 2006;(03): 175. doi: 10.3321/j.issn:1001-1668.2006.03.005. [in Chinese]
[24] Huang GP, Li CY,Liu LP, Li HM, Li HY, Peng GP. Screeningof Potent Active Components of Cimicifugae Rhizoma for Treating Hepatitis B Virus. Chinese Journal of Experimental Traditional Medical Formulae, 2013;19(21):231-35. doi:10.11653/syfj2013210231. [in Chinese]
[25] Sun H, Huang M, Yao N, Hu J, Li Y, Chen L, et al. The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells. Biochemical Pharmacology 2017; 146: 87-100. doi: 10.1016/j.bcp.2017.10.012.
[26] Wang X. The effect of puerarin injection on liver function and cell apoptosis in chronic hepatitis B. Chinese Journal of Misdiagnosis, 2009; 9(11): 2568-69. [in Chinese]
[27] Lin T, Wang K, Lin C, Chiang L, Chang J. Anti-Viral Activity of Water Extract of Paeonia lactiflora Pallas Against Human Respiratory Syncytial Virus in Human Respiratory Tract Cell Lines. The American Journal of Chinese Medicine 2013; 41 (3): 585-599. doi: 10.1142/S0192415X13500419.
[28] Cinatl J, Morgenstern B, Bauer G, Chandra P, Rabenau HF, Doerr HW. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. The Lancet 2003; 361 (9374): 2045-2046. doi: 10.1016/s0140-6736(03)13615-x.
[29] Crance J, Leveque F, Biziagos E, Van Cuyckgandre H, Jouan A, Deloince R. Studies on mechanism of action of glycyrrhizin against hepatitis a virus replication in vitro. Antiviral Research 1994; 23 (1): 63-76. doi: 10.1016/0166-3542(94)90033-7.
[30] Crance JM, Scaramozzino N, Jouan A, Garin D. Interferon, ribavirin, 6-azauridine and glycyrrhizin: antiviral compounds active against pathogenic flaviviruses. Antiviral Res 2003; 58 (1): 73-79. doi: 10.1016/s0166-3542(02)00185-7.