Public health-related misinformation spread rapidly in online networks, particularly, in social media during any disease outbreak. Misinformation of coronavirus disease 2019 (COVID-19) drug protocol or presentation of its treatment from untrusted sources have shown dramatic consequences on public health. Authorities are utilizing several surveillance tools to detect, and slow down the rapid misinformation spread online, still millions of misinformation are found online. However, there is no currently available tool for receiving real-time misinformation notification during online health or COVID-19 related inquiries. Our proposed novel combinational approach, where we have integrated machine learning techniques with novel search engine misinformation notifier extension (SEMiNExt), helps to understand which news or information is from unreliable sources in real-time. The extension filters the search results and shows notification beforehand; it is a new and unexplored approach to prevent the spread of misinformation. To validate the user query, SEMiNExt transfers the data to a machine learning algorithm or classifier which predicts the authenticity of the search inquiry and sends a binary decision as either true or false. The results show that the supervised learning algorithm works best when 80% of the data set have been used for training purpose. Also, 10-fold cross-validation demonstrate a maximum accuracy and F1-score of 84.3% and 84.1% respectively for the Decision Tree classifier while the K-nearest-neighbor (KNN) algorithm shows the least performance. The SEMiNExt approach has introduced the possibility to improve online health communication system by showing misinformation notifications in real-time which enables safer web-based searching while inquiring on health-related issues.