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Comparison of Optical Quality and Distinct Macular Thickness in Femtosecond Laser-Assisted versus Phacoemulsification Cataract Surgery
Huaijin Guan
Corresponding Author
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View the published version at BMC Ophthalmology.
Background: Optical quality and macular thickness changing optical quality is rarely reported after femtosecond laser-assisted cataract surgery (FLACS). In current research, we evaluated optical quality recovery and distinct macular thickness changes after FLACS and phacoemulsification cataract surgery (PCS). Methods: A total of 100 cataract patients (100 eyes) were included (50 eyes for the FLACS group and 50 eyes for the PCS group). Modulation transfer function (MTF), point spread function (PSF) and dysfunctional lens index (DLI) were measured by a ray-tracing aberrometer (iTrace). Uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA) were also assessed pre-operation,1 week and 1 month after surgery. The MTF values at spatial frequencies of 5, 10, 15, 20, 25 and 30 cycles/degree (c/d) were selected. We used optical coherence tomography (OCT) to assess the macular thickness of different regions pre-operatively and1month after the surgery. Results: In PCS group, we found the statistically significant differences between pre-operation and post-operation in DLI ( p <0.0001), PSF (strehl ratio, SR) ( p= 0.027) and MTF ( p =0.028), but not intraocular pressure (IOP) ( p =0.857). The differences between pre-operation and post-operation for DLI ( p =0.031), SR ( p =0.01) and IOP ( p =0.03), but not MTF ( p =0.128) were also found in FLACS group. The differences were statistically significant when the spatial frequencies were at 5, 10 and 25 ( p =0.013, 0.031 and 0.048) between pre-operation and post-operation in PCS group but not FLACS group at 1month. In PCS group, we found the differences between pre-operation and post-operation in nasal inter macular ring thickness (NIMRT) ( p =0.03), foveal volume (FV) ( p =0.034) and average retinal thickness (ART) ( p =0.025) but not FLACS group at 1month. Conclusion: FLACS is safe that did not cause significant increase of macular thickness in current study. However, it also cannot produce better optical quality. In contrast, PCS can produce macular thickness changes, but better optical quality recovery. The slightly retinal change may not affect optical quality.
Keywords
optical quality, macular thickness, femtosecond laser-assisted cataract surgery (FLACS), phacoemulsification cataract surgery (PCS), dysfunctional lens index (DLI), point spread function (PSF), modulation transfer function (MTF)
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CURRENT STATUS: Published
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Posted 15 Jan, 2020
Published
On 01 Feb, 2020
No community comments so far
Editorial decision: Accept
On 17 Jan, 2020
Editor assigned
On 14 Jan, 2020
Submission checks complete
On 13 Jan, 2020
Editor invited
On 13 Jan, 2020
No comments provided
Editorial decision: Minor revision
On 14 Jan, 2020
Editor assigned
On 10 Jan, 2020
Editor invited
On 09 Jan, 2020
Submission checks complete
On 24 Dec, 2019
No comments provided
Editorial decision: Major revision
On 10 Dec, 2019
Review #2 received
Received 09 Dec, 2019
Review #1 received
Received 06 Nov, 2019
Reviewer #3 agreed
On 25 Oct, 2019
Reviewer #2 agreed
On 24 Oct, 2019
Reviewer #1 agreed
On 07 Oct, 2019
Reviewers invited
Invitations sent on 07 Oct, 2019
Editor assigned
On 24 Sep, 2019
Submission checks complete
On 23 Sep, 2019
Editor invited
On 23 Sep, 2019
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Subject Areas
Ophthalmology
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This preprint is under consideration at BMC Ophthalmology. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Comparison of Optical Quality and Distinct Macular Thickness in Femtosecond Laser-Assisted versus Phacoemulsification Cataract Surgery
Huaijin Guan
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
Version 3
Posted 15 Jan, 2020
Published
On 01 Feb, 2020
No community comments so far
Editorial decision: Accept
On 17 Jan, 2020
Editor assigned
On 14 Jan, 2020
Submission checks complete
On 13 Jan, 2020
Editor invited
On 13 Jan, 2020
No comments provided
Editorial decision: Minor revision
On 14 Jan, 2020
Editor assigned
On 10 Jan, 2020
Editor invited
On 09 Jan, 2020
Submission checks complete
On 24 Dec, 2019
No comments provided
Editorial decision: Major revision
On 10 Dec, 2019
Review #2 received
Received 09 Dec, 2019
Review #1 received
Received 06 Nov, 2019
Reviewer #3 agreed
On 25 Oct, 2019
Reviewer #2 agreed
On 24 Oct, 2019
Reviewer #1 agreed
On 07 Oct, 2019
Reviewers invited
Invitations sent on 07 Oct, 2019
Editor assigned
On 24 Sep, 2019
Submission checks complete
On 23 Sep, 2019
Editor invited
On 23 Sep, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Ophthalmology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published version at BMC Ophthalmology.
Background: Optical quality and macular thickness changing optical quality is rarely reported after femtosecond laser-assisted cataract surgery (FLACS). In current research, we evaluated optical quality recovery and distinct macular thickness changes after FLACS and phacoemulsification cataract surgery (PCS). Methods: A total of 100 cataract patients (100 eyes) were included (50 eyes for the FLACS group and 50 eyes for the PCS group). Modulation transfer function (MTF), point spread function (PSF) and dysfunctional lens index (DLI) were measured by a ray-tracing aberrometer (iTrace). Uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA) were also assessed pre-operation,1 week and 1 month after surgery. The MTF values at spatial frequencies of 5, 10, 15, 20, 25 and 30 cycles/degree (c/d) were selected. We used optical coherence tomography (OCT) to assess the macular thickness of different regions pre-operatively and1month after the surgery. Results: In PCS group, we found the statistically significant differences between pre-operation and post-operation in DLI ( p <0.0001), PSF (strehl ratio, SR) ( p= 0.027) and MTF ( p =0.028), but not intraocular pressure (IOP) ( p =0.857). The differences between pre-operation and post-operation for DLI ( p =0.031), SR ( p =0.01) and IOP ( p =0.03), but not MTF ( p =0.128) were also found in FLACS group. The differences were statistically significant when the spatial frequencies were at 5, 10 and 25 ( p =0.013, 0.031 and 0.048) between pre-operation and post-operation in PCS group but not FLACS group at 1month. In PCS group, we found the differences between pre-operation and post-operation in nasal inter macular ring thickness (NIMRT) ( p =0.03), foveal volume (FV) ( p =0.034) and average retinal thickness (ART) ( p =0.025) but not FLACS group at 1month. Conclusion: FLACS is safe that did not cause significant increase of macular thickness in current study. However, it also cannot produce better optical quality. In contrast, PCS can produce macular thickness changes, but better optical quality recovery. The slightly retinal change may not affect optical quality.
Figure 1