Background: Compressed sensing magnetic resonance imaging (CS-MRI) is a promising technique for accelerating MRI speed. However, image quality in CS-MRI is still a pertinent problem. In particular, there is little work on reducing aliasing artefacts in compressed sensing diffusion tensor imaging (CS-DTI), which constitute a serious obstacle to obtaining high-quality images.
Method: We propose a CS-DTI de-aliasing method based on conditional generative adversarial (cGAN), called CS-GAN, to tackle de-aliasing problems in CS-DTI with highly undersampled k-space data. The method uses a nested-UNet based generator, a ResNet-based discriminator, and a content loss function defined in both image domain and frequency domain.
Result and Concludions: Compared to existing state-of-the-art de-aliasing methods based on deep learning, our method achieves superior imaging quality in terms of both diffusion weighted (DW) image quality and DTI diffusion metrics. Moreover, even at extremely low sampling ratio and low SNR, our method can still reconstruct texture details and spatial information.