In the beginning of March 2020, cases of CoVID-19 infections began rising worldwide, reacting to which the Government of India called for nationwide lockdown initially for March 25th to April 14th, 2020 and later extended it in phases till May 31st, 2020. Due to the forced restrictions pan-India on every level, the move led to drastic drop in pollution levels. The results demonstrated that during lockdown air quality is significantly improved and the pollution levels of PM2.5, PM10, SO2 and NO2 reduced drastically during the lockdown period than the preceding year for the same time frame. A direct relationship has been established between the high level of air pollutants (PM2.5, PM10, NO2 and SO2) and CoVID-19 infections being reported in these Indian cities. The correlation indicates that the air pollutants like PM2.5, PM10, NO2 and SO2 are aggravating the number of casualties due to the CoVID-19 infections. The high-level exposure of PM2.5 over a long period is found to be significantly correlated with the mortality per unit confirmed CoVID-19 cases as compared to other air pollutant parameters like PM10, NO2 and SO2.