Purpose To assess the early clinical outcomes of central hole phakic posterior chamber intraocular lens(ICL V4c) implantation for correction low and moderate myopia, and to explore the relationship among arch height, intraocular pressure(IOP), and central anterior chamber depth(ACD).
Methods This retrospective clinical study included 27 patients (47 eyes)which underwent implantation of ICL V4c for correction of myopia with spherical equivalent between -1.75 D and -6.0 D, From January 2017 to December 2018. Preoperative corrected distance visual acuity (CDVA), postoperative uncorrected visual acuity (UCVA), and IOP were evaluated at one day, one week, three mouths, six mouths, and twelve months. ACD, arch height, and endothelial cell density (ECD) were evaluated at one, three and twelve months.
Results At 1 year follow-up, the UCVA of 75% eyes are larger than the preoperative CDVA, and that of 25% eyes are equal to the preoperative CDVA. The postoperative UCVA of the patients was higher than the preoperative BCVA and showed a stable trend. There was no significant difference in ECD (P > 0.05). One month after surgery, the arch height was (0.77 ±0.32) mm, and decreased to (0.63 ± 0.26) mm at the one-year after surgery. ACD was (3.24±0.25) mm in the preoperative, decreased significantly to (2.05±0.39) mm at one month, and rose to (2.2± 0.39) mm at one year after surgery. There was no significant correlation between IOP and ACD and arch height at 1 month and 1 year after operation. The correlation coefficient between ACD and arch height was -0.72 at 1 month after surgery, and it was -0.71 at 1 year. One patient had visual fatigue, one patient had glare, and none of subjects developed cataract, glaucoma and decompensation of corneal endothelium.
Conclusion ICL implantation is a safe, effective and stable method for the correction of low and moderate myopia, and it may be a good alternative for patients with low and moderate myopia who cannot undergo corneal refractive surgery.