1.Thomma BP, Nurnberger T, Joosten MH: Of PAMPs and effectors: the blurred PTI-ETI dichotomy. The Plant cell 2011, 23(1):4–15.
2.Newman MA, Sundelin T, Nielsen JT, Erbs G: MAMP (microbe-associated molecular pattern) triggered immunity in plants. Front Plant Sci 2013, 4:139.
3.Zipfel C: Plant pattern-recognition receptors. Trends in immunology 2014, 35(7):345–351.
4.Jurca ME, Bottka S, Feher A: Characterization of a family of Arabidopsis receptor-like cytoplasmic kinases (RLCK class VI). Plant cell reports 2008, 27(4):739–748.
5.Greeff C, Roux M, Mundy J, Petersen M: Receptor-like kinase complexes in plant innate immunity. Front Plant Sci 2012, 3:209.
6.Liu T, Liu Z, Song C, Hu Y, Han Z, She J, Fan F, Wang J, Jin C, Chang J et al: Chitin-induced dimerization activates a plant immune receptor. Science (New York, NY) 2012, 336(6085):1160–1164.
7.Cao Y, Liang Y, Tanaka K, Nguyen CT, Jedrzejczak RP, Joachimiak A, Stacey G: The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1. eLife 2014, 3.
8.Lin W, Li B, Lu D, Chen S, Zhu N, He P, Shan L: Tyrosine phosphorylation of protein kinase complex BAK1/BIK1 mediates Arabidopsis innate immunity. Proc Natl Acad Sci U S A 2014, 111(9):3632–3637.
9.Shi H, Shen Q, Qi Y, Yan H, Nie H, Chen Y, Zhao T, Katagiri F, Tang D: BR-SIGNALING KINASE1 physically associates with FLAGELLIN SENSING2 and regulates plant innate immunity in Arabidopsis. The Plant cell 2013, 25(3):1143–1157.
10.Kobe B, Deisenhofer J: Proteins with leucine-rich repeats. Current opinion in structural biology 1995, 5(3):409–416.
11.Kim SH, Kwon SI, Saha D, Anyanwu NC, Gassmann W: Resistance to the Pseudomonas syringae effector HopA1 is governed by the TIR-NBS-LRR protein RPS6 and is enhanced by mutations in SRFR1. Plant physiology 2009, 150(4):1723–1732.
12.Van der Biezen EA, Jones JD: Plant disease-resistance proteins and the gene-for-gene concept. Trends in biochemical sciences 1998, 23(12):454–456.
13.Sekhwal MK, Li P, Lam I, Wang X, Cloutier S, You FM: Disease Resistance Gene Analogs (RGAs) in Plants. International journal of molecular sciences 2015, 16(8):19248–19290.
14.Song D, Li G, Song F, Zheng Z: Molecular characterization and expression analysis of OsBISERK1, a gene encoding a leucine-rich repeat receptor-like kinase, during disease resistance responses in rice. Mol Biol Rep 2008, 35(2):275–283.
15.Bella J, Hindle KL, McEwan PA, Lovell SC: The leucine-rich repeat structure. Cellular and molecular life sciences: CMLS 2008, 65(15):2307–2333.
16.Williams SJ, Yin L, Foley G, Casey LW, Outram MA, Ericsson DJ, Lu J, Boden M, Dry IB, Kobe B: Structure and Function of the TIR Domain from the Grape NLR Protein RPV1. Front Plant Sci 2016, 7:1850.
17.Gou X, He K, Yang H, Yuan T, Lin H, Clouse SD, Li J: Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana. BMC genomics 2010, 11:19.
18.Chinchilla D, Bauer Z, Regenass M, Boller T, Felix G: The Arabidopsis receptor kinase FLS2 binds flg22 and determines the specificity of flagellin perception. The Plant cell 2006, 18(2):465–476.
19.Hong JK, Hwang IS, Hwang BK: Functional roles of the pepper leucine-rich repeat protein and its interactions with pathogenesis-related and hypersensitive-induced proteins in plant cell death and immunity. Planta 2017, 246(3):351–364.
20.Cheng W, Xiao Z, Cai H, Wang C, Hu Y, Xiao Y, Zheng Y, Shen L, Yang S, Liu Z et al: A novel leucine-rich repeat protein, CaLRR51, acts as a positive regulator in the response of pepper to Ralstonia solanacearum infection. Molecular plant pathology 2017, 18(8):1089–1100.
21.Afzal AJ, Wood AJ, Lightfoot DA: Plant receptor-like serine threonine kinases: roles in signaling and plant defense. Molecular plant-microbe interactions: MPMI 2008, 21(5):507–517.
22.Li J, Wen J, Lease KA, Doke JT, Tax FE, Walker JC: BAK1, an Arabidopsis LRR receptor-like protein kinase, interacts with BRI1 and modulates brassinosteroid signaling. Cell 2002, 110(2):213–222.
23.Nam KH, Li J: BRI1/BAK1, a receptor kinase pair mediating brassinosteroid signaling. Cell 2002, 110(2):203–212.
24.Albert I, Zhang L, Bemm H, Nurnberger T: Structure-Function Analysis of Immune Receptor AtRLP23 with Its Ligand nlp20 and Coreceptors AtSOBIR1 and AtBAK1. Molecular plant-microbe interactions: MPMI 2019, 32(8):1038–1046.
25.Cui HR, Zhang ZR, Lv W, Xu JN, Wang XY: Genome-wide characterization and analysis of F-box protein-encoding genes in the Malus domestica genome. Molecular genetics and genomics: MGG 2015, 290(4):1435–1446.
26.Kuchay S, Duan SS, Schenkein E, Peschiaroli A, Saraf A, Florens L, Washburn MP, Pagano M: FBXL2-and PTPL1-mediated degradation of p110-free p85 beta regulatory subunit controls the PI(3)K signalling cascade. Nat Cell Biol 2013, 15(5):472-+.
27.Jia Q, Xiao ZX, Wong FL, Sun S, Liang KJ, Lam HM: Genome-Wide Analyses of the Soybean F-Box Gene Family in Response to Salt Stress. International journal of molecular sciences 2017, 18(4).
28.Song JB, Wang YX, Li HB, Li BW, Zhou ZS, Gao S, Yang ZM: The F-box family genes as key elements in response to salt, heavy mental, and drought stresses in Medicago truncatula. Functional & integrative genomics 2015, 15(4):495–507.
29.Hu Z, Keceli MA, Piisila M, Li J, Survila M, Heino P, Brader G, Palva ET, Li J: F-box protein AFB4 plays a crucial role in plant growth, development and innate immunity. Cell research 2012, 22(4):777–781.
30.Angot A, Peeters N, Lechner E, Vailleau F, Baud C, Gentzbittel L, Sartorel E, Genschik P, Boucher C, Genin S: Ralstonia solanacearum requires F-box-like domain-containing type III effectors to promote disease on several host plants. Proc Natl Acad Sci U S A 2006, 103(39):14620–14625.
31.Li LQ, Pan D, Chen H, Zhang L, Xie WJ: F-box protein FBXL2 inhibits gastric cancer proliferation by ubiquitin-mediated degradation of forkhead box M1. FEBS letters 2016, 590(4):445–452.
32.Chen BB, Glasser JR, Coon TA, Mallampalli RK: Skp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesis. Cell death & disease 2013, 4:e759.
33.Tosto G, Fu H, Vardarajan BN, Lee JH, Cheng R, Reyes-Dumeyer D, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Elkind MS et al: F-box/LRR-repeat protein 7 is genetically associated with Alzheimer’s disease. Annals of clinical and translational neurology 2015, 2(8):810–820.
34.Tran DTN, Chung EH, Habring-Muller A, Demar M, Schwab R, Dangl JL, Weigel D, Chae E: Activation of a Plant NLR Complex through Heteromeric Association with an Autoimmune Risk Variant of Another NLR. Current biology: CB 2017, 27(8):1148–1160.
35.Takken FL, Albrecht M, Tameling WI: Resistance proteins: molecular switches of plant defence. Current opinion in plant biology 2006, 9(4):383–390.
36.Bentham A, Burdett H, Anderson PA, Williams SJ, Kobe B: Animal NLRs provide structural insights into plant NLR function. Annals of botany 2017, 119(5):827–702.
37.Chakraborty J, Jain A, Mukherjee D, Ghosh S, Das S: Functional diversification of structurally alike NLR proteins in plants. Plant Sci 2018, 269:85–93.
38.Zhao Y, Weng Q, Song J, Ma H, Yuan J, Dong Z, Liu Y: Bioinformatics Analysis of NBS-LRR Encoding Resistance Genes in Setaria italica. Biochem Genet 2016, 54(3):232–248.
39.Zhu X, Lu C, Du L, Ye X, Liu X, Coules A, Zhang Z: The wheat NB-LRR gene TaRCR1 is required for host defence response to the necrotrophic fungal pathogen Rhizoctonia cerealis. Plant biotechnology journal 2017, 15(6):674–687.
40.Xing L, Hu P, Liu J, Witek K, Zhou S, Xu J, Zhou W, Gao L, Huang Z, Zhang R et al: Pm21 from Haynaldia villosa Encodes a CC-NBS-LRR Protein Conferring Powdery Mildew Resistance in Wheat. Molecular plant 2018, 11(6):874–878.
41.Li X, Zhang Y, Yin L, Lu J: Overexpression of pathogen-induced grapevine TIR-NB-LRR gene VaRGA1 enhances disease resistance and drought and salt tolerance in Nicotiana benthamiana. Protoplasma 2017, 254(2):957–969.
42.Xun H, Yang X, He H, Wang M, Guo P, Wang Y, Pang J, Dong Y, Feng X, Wang S et al: Over-expression of GmKR3, a TIR-NBS-LRR type R gene, confers resistance to multiple viruses in soybean. Plant molecular biology 2019, 99(1–2):95–111.
43.Chuang MF, Ni HF, Yang HR, Shu SL, Lai SY, Jiang YL: First report of stem canker disease of pitaya (Hylocereus undatus and H. polyrhizus) caused by Neoscytalidium dimidiatum in Taiwan. Plant Disease 2012, 96(6):906–906.
44.Xu M, Peng Y, Qi Z, Yan Z, Yang L, He M-D, Li Q-X, Liu C-L, Ruan Y-Z, Wei S-S et al: Identification of Neoscytalidium dimidiatum causing canker disease of pitaya in Hainan, China. Australasian Plant Pathology 2018, 47(5):547–553.
45.Xu M, Liu CL, Luo J, Qi Z, Yan Z, Fu Y, Wei SS, Tang H: Transcriptomic de novo analysis of pitaya (Hylocereus polyrhizus) canker disease caused by Neoscytalidium dimidiatum. BMC genomics 2019, 20(1):10.
46.Tamura K, Stecher G, Peterson D, Filipski A, Kumar S: MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Molecular biology and evolution 2013, 30(12):2725–2729.
47.Schallus T, Jaeckh C, Feher K, Palma AS, Liu Y, Simpson JC, Mackeen M, Stier G, Gibson TJ, Feizi T et al: Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation. Molecular biology of the cell 2008, 19(8):3404–3414.
48.Robert-Seilaniantz A, Navarro L, Bari R, Jones JD: Pathological hormone imbalances. Current opinion in plant biology 2007, 10(4):372–379.
49.Padmanabhan M, Cournoyer P, Dinesh-Kumar SP: The leucine-rich repeat domain in plant innate immunity: a wealth of possibilities. Cellular microbiology 2009, 11(2):191–198.
50.Kang UB, Marto JA: Leucine-rich repeat kinase 2 and Parkinson’s disease. Proteomics 2017, 17(1–2).
51.Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O’Morain CA, Gassull M et al: Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn’s disease. Nature 2001, 411(6837):599–603.
52.Dangl JL, Jones JD: Plant pathogens and integrated defence responses to infection. Nature 2001, 411(6839):826–833.
53.Forsthoefel NR, Dao TP, Vernon DM: PIRL1 and PIRL9, encoding members of a novel plant-specific family of leucine-rich repeat proteins, are essential for differentiation of microspores into pollen. Planta 2010, 232(5):1101–1114.
54.Torii KU: Leucine-rich repeat receptor kinases in plants: structure, function, and signal transduction pathways. International review of cytology 2004, 234:1–46.
55.Chaparro-Garcia A, Wilkinson RC, Gimenez-Ibanez S, Findlay K, Coffey MD, Zipfel C, Rathjen JP, Kamoun S, Schornack S: The receptor-like kinase SERK3/BAK1 is required for basal resistance against the late blight pathogen phytophthora infestans in Nicotiana benthamiana. PLoS One 2011, 6(1):e16608.
56.Clark SE, Running MP, Meyerowitz EM: CLAVATA1, a regulator of meristem and flower development in Arabidopsis. Development (Cambridge, England) 1993, 119(2):397–418.
57.Jeong S, Trotochaud AE, Clark SE: The Arabidopsis CLAVATA2 gene encodes a receptor-like protein required for the stability of the CLAVATA1 receptor-like kinase. The Plant cell 1999, 11(10):1925–1934.
58.Rojo E, Sharma VK, Kovaleva V, Raikhel NV, Fletcher JC: CLV3 is localized to the extracellular space, where it activates the Arabidopsis CLAVATA stem cell signaling pathway. The Plant cell 2002, 14(5):969–977.
59.Liu W, Liu J, Triplett L, Leach JE, Wang GL: Novel insights into rice innate immunity against bacterial and fungal pathogens. Annual review of phytopathology 2014, 52:213–241.
60.Yi SY, Kwon SY: How does SA signaling link the Flg22 responses? Plant signaling & behavior 2014, 9(11):e972806.
61.An C, Mou Z: Salicylic acid and its function in plant immunity. Journal of integrative plant biology 2011, 53(6):412–428.
62.Aarts N, Metz M, Holub E, Staskawicz BJ, Daniels MJ, Parker JE: Different requirements for EDS1 and NDR1 by disease resistance genes define at least two R gene-mediated signaling pathways in Arabidopsis. Proc Natl Acad Sci U S A 1998, 95(17):10306–10311.
63.Kim SY, Shang Y, Joo SH, Kim SK, Nam KH: Overexpression of BAK1 causes salicylic acid accumulation and deregulation of cell death control genes. Biochemical and biophysical research communications 2017, 484(4):781–786.
64.Ahmad P, Rasool S, Gul A, Sheikh SA, Akram NA, Ashraf M, Kazi AM, Gucel S: Jasmonates: Multifunctional Roles in Stress Tolerance. Front Plant Sci 2016, 7:813.
65.Chang X, Seo M, Takebayashi Y, Kamiya Y, Riemann M, Nick P: Jasmonates are induced by the PAMP flg22 but not the cell death-inducing elicitor Harpin in Vitis rupestris. Protoplasma 2017, 254(1):271–283.
66.Dong T, Park Y, Hwang I: Abscisic acid: biosynthesis, inactivation, homoeostasis and signalling. Essays in biochemistry 2015, 58:29–48.
67.Li Y, Wang C, Liu X, Song J, Li H, Sui Z, Zhang M, Fang S, Chu J, Xin M et al: Up-regulating the abscisic acid inactivation gene ZmABA8ox1b contributes to seed germination heterosis by promoting cell expansion. J Exp Bot 2016, 67(9):2889–2900.
68.Yang W, Zhang W, Wang X: Post-translational control of ABA signalling: the roles of protein phosphorylation and ubiquitination. Plant biotechnology journal 2017, 15(1):4–14.
69.Ning Y, Liu W, Wang GL: Balancing Immunity and Yield in Crop Plants. Trends in plant science 2017, 22(12):1069–1079.
70.White EJ, Venter M, Hiten NF, Burger JT: Modified Cetyltrimethylammonium bromide method improves robustness and versatility: The benchmark for plant RNA extraction. Biotechnology Journal 2008, 3(11):1424–1428.
71.Fengxia Y XW, Guoli G, Jin T: Cloning and sequence analysis of housekeeping genes Actin and UBQ from pitaya. Guizhou Agricultural Sciences 2013, 41(9):4.