Large mid-upper arm circumference is associated with metabolic syndrome in middle-aged and elderly individuals: a community-based study
Background The mid-upper arm circumference (MUAC) is a proxy for subcutaneous fat in the upper body and is a reliable screening measure for identifying individuals with abnormal regional fat distribution. The purpose of this study was to evaluate the association between MUAC and metabolic syndrome (MetS) in middle-aged and elderly individuals.
Methods We measured the MUAC in a cross-sectional sample with a total of 9787 subjects aged 40 years and older. The measurement of MUAC is performed on the right arm using a non‐elastic tape held midway between the acromion and the olecranon processes in duplicate, with the arm hanging loosely at the side of the body. The MetS was defined according to the Joint Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention.
Results MUAC was positively correlated with waist circumference (r=0.437, P<0.001), BMI (r=0.334, P<0.001), fasting insulin (r=0.348, P<0.001), HOMA-IR (r=0.134, P< 0.001), triglycerides (r=0.138, P<0.001), SBP (r=0.124, P< 0.001), and DBP (r= 0.123, P<0.001), and inversely correlated with adiponectin (r=-0.147, P < 0.001) and HDL-cholesterol (r=-0.176, P<0.001) after adjusting for age and gender. Compared with the lowest quartile group, the odds ratios were substantially higher for MetS (OR 1.77; 95% CI 1.51-2.09, P for trend<0.001) in the highest MUAC quartile group after adjustment for potential cofounder.
Conclusion Large mid-upper arm circumference is significantly associated with metabolic syndrome in middle-aged and elderly individuals .
Figure 1
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Large mid-upper arm circumference is associated with metabolic syndrome in middle-aged and elderly individuals: a community-based study
Posted 29 May, 2020
On 21 May, 2020
On 20 May, 2020
On 20 May, 2020
On 27 Apr, 2020
On 24 Apr, 2020
On 23 Apr, 2020
On 23 Apr, 2020
On 02 Apr, 2020
On 31 Mar, 2020
On 30 Mar, 2020
On 30 Mar, 2020
On 18 Mar, 2020
Received 10 Mar, 2020
On 27 Feb, 2020
Received 27 Feb, 2020
On 24 Feb, 2020
Invitations sent on 24 Feb, 2020
On 23 Feb, 2020
On 22 Feb, 2020
On 22 Feb, 2020
Received 22 Jan, 2020
On 22 Jan, 2020
Received 21 Jan, 2020
Received 19 Jan, 2020
On 13 Jan, 2020
On 13 Jan, 2020
On 12 Jan, 2020
On 11 Jan, 2020
On 28 Oct, 2019
Received 21 Oct, 2019
On 20 Oct, 2019
On 15 Oct, 2019
Invitations sent on 15 Oct, 2019
On 09 Oct, 2019
On 09 Oct, 2019
On 01 Oct, 2019
Background The mid-upper arm circumference (MUAC) is a proxy for subcutaneous fat in the upper body and is a reliable screening measure for identifying individuals with abnormal regional fat distribution. The purpose of this study was to evaluate the association between MUAC and metabolic syndrome (MetS) in middle-aged and elderly individuals.
Methods We measured the MUAC in a cross-sectional sample with a total of 9787 subjects aged 40 years and older. The measurement of MUAC is performed on the right arm using a non‐elastic tape held midway between the acromion and the olecranon processes in duplicate, with the arm hanging loosely at the side of the body. The MetS was defined according to the Joint Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention.
Results MUAC was positively correlated with waist circumference (r=0.437, P<0.001), BMI (r=0.334, P<0.001), fasting insulin (r=0.348, P<0.001), HOMA-IR (r=0.134, P< 0.001), triglycerides (r=0.138, P<0.001), SBP (r=0.124, P< 0.001), and DBP (r= 0.123, P<0.001), and inversely correlated with adiponectin (r=-0.147, P < 0.001) and HDL-cholesterol (r=-0.176, P<0.001) after adjusting for age and gender. Compared with the lowest quartile group, the odds ratios were substantially higher for MetS (OR 1.77; 95% CI 1.51-2.09, P for trend<0.001) in the highest MUAC quartile group after adjustment for potential cofounder.
Conclusion Large mid-upper arm circumference is significantly associated with metabolic syndrome in middle-aged and elderly individuals .
Figure 1