The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in Japan
Objective
Pneumonia is a common but serious illness that continues to present significant morbidity and mortality. Although the effect of severity at admission on outcome has been well reported, the role of comorbidity is still not widely understood. The Charlson Comorbidity Index measures comorbidity with a well-established history of predicting long-term outcome but its utility in pneumonia prognosis is still limited. Here, we use the Charlson Comorbidity Index and hospital surveillance data to investigate associations between comorbidities and in-hospital mortality due to community-acquired pneumonia.
Results
Among the 535 eligible adult patients (69.0% male, median [IQR] age, 79 [70-84] years), 100 (18.7%) acquired severe to extremely severe pneumonia. The median [IQR] CCI was 1[1-3]. Malignancy (129 of 535, 24.1%), chronic pulmonary diseases (113 of 535, 21.1%) and congestive heart failure (103 of 535, 19.3%) were frequent. Higher Charlson Comorbidity Index scores were associated with higher risk of in-hospital mortality (OR 1.28; 95% CI 1.07-1.53). These results support the inclusion of comorbid burden in predicting community-acquired pneumonia outcome.
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Posted 18 Dec, 2019
On 19 Dec, 2019
On 08 Dec, 2019
On 06 Dec, 2019
On 04 Dec, 2019
On 29 Nov, 2019
On 28 Nov, 2019
On 28 Nov, 2019
On 15 Nov, 2019
Received 22 Oct, 2019
On 11 Oct, 2019
On 11 Oct, 2019
On 11 Oct, 2019
Invitations sent on 11 Oct, 2019
On 11 Oct, 2019
On 04 Oct, 2019
The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in Japan
Posted 18 Dec, 2019
On 19 Dec, 2019
On 08 Dec, 2019
On 06 Dec, 2019
On 04 Dec, 2019
On 29 Nov, 2019
On 28 Nov, 2019
On 28 Nov, 2019
On 15 Nov, 2019
Received 22 Oct, 2019
On 11 Oct, 2019
On 11 Oct, 2019
On 11 Oct, 2019
Invitations sent on 11 Oct, 2019
On 11 Oct, 2019
On 04 Oct, 2019
Objective
Pneumonia is a common but serious illness that continues to present significant morbidity and mortality. Although the effect of severity at admission on outcome has been well reported, the role of comorbidity is still not widely understood. The Charlson Comorbidity Index measures comorbidity with a well-established history of predicting long-term outcome but its utility in pneumonia prognosis is still limited. Here, we use the Charlson Comorbidity Index and hospital surveillance data to investigate associations between comorbidities and in-hospital mortality due to community-acquired pneumonia.
Results
Among the 535 eligible adult patients (69.0% male, median [IQR] age, 79 [70-84] years), 100 (18.7%) acquired severe to extremely severe pneumonia. The median [IQR] CCI was 1[1-3]. Malignancy (129 of 535, 24.1%), chronic pulmonary diseases (113 of 535, 21.1%) and congestive heart failure (103 of 535, 19.3%) were frequent. Higher Charlson Comorbidity Index scores were associated with higher risk of in-hospital mortality (OR 1.28; 95% CI 1.07-1.53). These results support the inclusion of comorbid burden in predicting community-acquired pneumonia outcome.