Despite being a liquefaction susceptible zone, Kathmandu Valley soil in Nepal has limited studies on liquefaction potential and most of them are based on the deterministic approach. Although this method is widely used, it ignores the uncertainties of seismic parameters such as peak ground acceleration, amax, and earthquake magnitude, Mw as well as the inherent variabilities of soil layers, in-situ testing procedures, and geotechnical properties. On the other hand, the probabilistic approach helps assess the liquefaction potential by considering all these uncertainties. In this study, we assess the liquefaction hazard in the Kathmandu Valley using the first-order second-moment (FOSM) method as a probabilistic approach for liquefaction hazard assessment. The assessment is done for three likely-to-recur scenario earthquakes utilizing the geotechnical data of 1510 boreholes. The soils are characterized geotechnically to further assess susceptibility criteria of liquefaction in the valley. The assessment reveals that the central part of the valley is more vulnerable to liquefaction than other parts and the liquefaction probability increases with increasing depth up to 9 m, after which has geared down the value. Moreover, a relationship between the probability of liquefaction (PL) and the factor of safety (FS) against liquefaction is established. The hazard maps prepared for different earthquake scenarios can be useful for future infrastructure planning in Kathmandu Valley.