Polymicrobial periprosthetic joint infection is a subset of periprosthetic joint infection and indicates disastrous outcomes. However, the incidence of polymicrobial PJI can be underestimated so we perform a single-center retrospective study with an intention to predict the incidence of polymicrobial PJI based on culture results.
Materials and methods
Medical records about 153 patients with PJI between 2017/1/1 and 2018/12/31 in a joint center were selected retrospectively. Multivariable analysis was utilized to evaluate the association between various pathogens and polymicrobial PJI.
Staphylococcus aureus (OR:3.83, 95%CI(1.30,11.27), p-value = 0.015 ), coagulase negative staphylococci (OR: 2.68 ,95%CI: (1.10, 6.25), p-value = 0.028), Enterococcus spp (OR:6.46;95%CI(1.35,30.87),P-value = 0.020)andStreptococcusspp(OR:19.38, 95%CI:(3.57,105.21), p-value = 0.001) indicate higher risk of polymicrobial pathogens compared with other pathogens
Streptococcus spp and Enterococcus spp are associated with higher risk of polymicrobial PJI and more pathogens are like to be found in additional culture when these pathogens are detected by a single culture.