Designing land-based climate stabilisation strategies demands changes in land use management or new areas to grow biomass sustainably, without reducing food supply or damaging natural ecosystems. Here we integrated, into a generalizable framework, the mapping of a set of biophysical (climatic and edaphic) and land conservation constraints to identify the pairing of target areas with suitable plant species, and quantify their contributions to long-term soil carbon sequestration, including losses from rain-driven erosion. The proposed framework represents a refinement to previous global mapping exercises, which seldom consider pedo-climatic constraints, plant species tolerances and world protected areas. We demonstrated the applicability of the framework through a global case study by mapping target areas featuring low soil organic carbon stocks (≤50 t SOC ha-1) and producing quantifiable soil carbon sequestration potentials of best matches. Preliminary target areas were mapped at a 30 arc-sec resolution, and then consolidated per geographical and environmental boundaries (geopolitical world regions x global ecological zones).