Determine fungicidal activity of five disinfectants on Candida auris of clinical and environmental origin. Assess fungicidal efficiency of each disinfectants on the microorganism. Calculate percentage of efficiency (% E) of each disinfectants on Candida strain and determine specific death rate (k) and decimal reduction time for the microorganism. An analytic and experimental research with quantitative methods. We realized a strains workbench by culturing it in corresponding culture media. Analysis was a challenge essay, performed on four surfaces and at different exposure times; 1, 5, 15 and 30 minutes of contact between disinfectant and yeast. Once disinfection process was carried out, what was expected was that after 15 minutes of contact between the yeasts and the disinfectants, a percentage of inhibition of the microorganism between 90 and 95% was presented, thus guaranteeing the duration of elimination of the infectious agent by disinfectants. Results shows that after one minute of contact between Candida auris and the disinfectant in a gloved hand, there was a removal of the yeast, when the clinical and environmental strain were analyzed. Data showing disinfectants efficiency percentages greater than 90% over strains of Candida used in the study. Decimal reduction times in seconds of the strains of Candida against the disinfectants used in the study were between 9.3 and 14.04 s. It was possible to evaluate effectiveness by means inhibition percentage of each disinfectants on the strains of Candida auris of clinical and environmental origin. Similarly, specific death rate and decimal reduction time in seconds were determined for strains under study.