1. Lee YK, Sohn JH, Han JS, Park YJ, Jeon YG, Ji Y, Dalen KT, Sztalryd C, Kimmel AR, Kim JB. Perilipin 3 Deficiency Stimulates Thermogenic Beige Adipocytes Through PPARα Activation. Diabetes 2018;67(5):791-804.
2. Heeren J, Scheja L. Brown adipose tissue and lipid metabolism. Curr Opin Lipidol 2018;29(3):180-185.
3. Shan L, Yu XC, Liu Z, Hu Y, Sturgis LT, Miranda ML, Liu Q. The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms. J Biol Chem 2009;16;284(3):1419-1424.
4. Finn PF, Dice JF. Proteolytic and lipolytic responses to starvation. Nutrition 2006;22(7-8):830-844.
5. Lee JN, Dutta RK, Kim SG, Lim JY, Kim SJ, Choe SK, Yoo KW, Song SR, Park DS, So HS, Park Ra. Fenofibrate, a peroxisome proliferator-activated receptor α ligand, prevents abnormal liver function induced by a fasting-refeeding process, Biochem Biophys Res Commun 2013;442(1-2):22-27.
6. Wang Y, McNutt MC, Banfi S, Levin MG, Holland WL, Gusarova V, Gromada J, Cohen JC, Hobbs HH. Hepatic ANGPTL3 regulates adipose tissue energy homeostasis. Proc Natl Acad Sci U S A 2015;112(37):11630-11635.
7. Santulli G. Angiopoietin-like proteins: a comprehensive look. Front Endocrinol (Lausanne) (2014);5:4.
8. Quagliarini F, Wang Y, Kozlitina J, Grishin NV, Hyde R, Boerwinkle E, Valenzuela DM, Murphy AJ, Cohen JC, Hobbs HH. Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A 2012;109(48):19751-19756.
9. Koishi R, Ando Y, Ono M, Shimamura M, Yasumo H, Fujiwara T, Horikoshi H, Furukawa H. Angptl3 regulates lipid metabolism in mice. Nat Genet 2002;30(2):151-157.
10. Conklin D, Gilbertson D, Taft DW, Maurer MF, Whitmore TE, Smith DL, Walker KM, Chen LH, Wattler S, Nehls M, Lewis KB. Identification of a mammalian angiopoietin-related protein expressed specifically in liver. Genomics 1999;62(3):477-482.
11. Dijk W, Heine M, Vergnes L, Boon MR, Schaart G, Hesselink MK, Reue K, van Marken Lichtenbelt WD, Olivecrona G, Rensen PC, Heeren J, Kersten S. ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure. Elife 2015;4.
12. Kersten S, Mandard S, Tan NS, Escher P, Metzger D, Chambon P, Gonzalez FJ, Desvergne B, Wahli W. Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J Biol Chem 2000;275(37):28488-28493.
13. Krawczyk SA, Haller JF, Ferrante T, Zoeller RA, Corkey BE. Reactive oxygen species facilitate translocation of hormone sensitive lipase to the lipid droplet during lipolysis in human differentiated adipocytes. PLoS ONE 2012;7(4).
14. Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM. Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP.1 Nature 2016;532:112-116.
15. Shabalina IG, Vrbacký M, Pecinová A, Kalinovich AV, Drahota Z, Houštěk J, Mráček T, Cannon B, Nedergaard J. ROS production in brown adipose tissue mitochondria: the question of UCP1-dependence. Biochim Biophys Acta 2014;1837(12):2017-2030.
16. Dlasková A, Clarke KJ, Porter RK. The role of UCP 1 in production of reactive oxygen species by mitochondria isolated from brown adipose tissue. Biochim Biophys Acta 2010;1797:1470-1476.
17. Phaniendra A, Jestadi DB, Periyasamy L. Free radicals: properties, sources, targets, and their implication in various diseases. Indian J Clin Biochem 2015;30(1):11-26.
18. Schrader M, Fahimi HD. Peroxisomes and oxidative stress. Biochim Biophys Acta 2006;1763(12):1755-1766.
19. Ho YS, Xiong Y, Ma W, Spector A, Ho DS. Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury. J Biol Chem 2004;279(31):32804-32812.
20. Takahara S, Miyamoto H. Three cases of progressive oral gangrene due to lack of catalase in the blood. Nippon Jibi-Inkoka Gakkai Kaiho 1948;51:163.
21. Lee JN, Dutta RK, Maharjan Y, Liu ZQ, Lim JY, Kim SJ, Cho DH, So HS, Choe SK, Park R. Catalase inhibition induces pexophagy through ROS accumulation. Biochem Biophys Res Commun 2018;501(3):696-702.
22. Dutta RK, Maharjan Y, Lee JN, Park C, Ho YS, Park R. Catalase deficiency induces reactive oxygen species mediated pexophagy and cell death in the liver during prolonged fasting. Biofactors 2021;47(4):1-14.
23. Fransen M, Nordgren M, Wang B, Apanasets O. Role of peroxisomes in ROS/RNS-metabolism: implications for human disease. Biochim Biophys Acta 2012;1822(9):1363-1373.
24. Yao C, Behring JB, Shao D, Sverdlov AL, Whelan SA, Elezaby A, Yin X, Siwik DA, Seta F, Costello CE, Cohen RA, Matsui R, Colucci WS, McComb ME, Bachschmid MM. Overexpression of catalase diminishes oxidative cysteine modifications of cardiac proteins. PLoS One 2015;10(12).
25. Paglialunga S, Ludzki A, Root-McCaig J, Holloway GP. In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice. Diabetologia 2015;58(5):1071-1080.
26. Amos DL, Robinson T, Massie MB, Cook C, Hoffsted A, Crain C, Santanam N. Catalase overexpression modulates metabolic parameters in a new 'stress-less' leptin-deficient mouse model. Biochim Biophys Acta Mol Basis Dis 2017;1863(9):2293-2306.
27. Hashimoto T, Cook WS, Qi C, Yeldandi AV, Reddy JK, Rao MS. Defect in peroxisome proliferator-activated receptor a-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting. J Biol Chem 2000;275(37): 28918-28928.
28. Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferator–activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 1999;103(11):1489-1498.
29. Chondronikola M, Volpi E, Børsheim E, Porter C, Saraf MK, Annamalai P, Yfanti C, Chao T, Wong D, Shinoda K, Labbė SM, Hurren NM, Cesani F, Kajimura S, Sidossis LS. Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans. Cell Metab 2016;23(6):1200-1206.
30. Shin H, Ma Y, Chanturiya T, Cao Q, Wang Y, Kadegowda AKG, Jackson R, Rumore D, Xue B, Shi H, Gavrilova O, Yu L. Lipolysis in brown adipocytes is not essential for cold-induced thermogenesis in mice. Cell Metab 2017;26(5):764-777.
31. Doan KV, Kinyua AW, Yang DJ, Ko CM, Moh SH, Shong KE, Kim H, Park SK, Kim DH, Kim I, Paik JH, DePinho RA, Yoon SG, Kim IY, Seong JK, Choi YH, Kim KW. FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase. Nat Commun 2016;7.
32. Szentirmai É, Kapás L. The role of the brown adipose tissue in β3-adrenergic receptor activation-induced sleep, metabolic and feeding responses. Sci Rep 2017;7(1).
33. Young SG, Zechner R. Biochemistry and pathophysiology of intravascular and intracellular lipolysis. Genes Dev 2013;27(5)459-484.
34. Townsend KL, Tseng YH. Brown fat fuel utilization and thermogenesis. Trends Endocrinol Metab 2014;25(4)168-177.
35. Abumrad NA. The liver as a hub in thermogenesis. Cell Metab 2017;26(3):454-455.
36. Cannon B, Nedergaard J. What Ignites UCP1? Cell Metab 2017;26(5): 697-698.
37. Serviddio G, Bellanti F, Vendemiale G. Free radical biology for medicine: learning from nonalcoholic fatty liver disease. Free Radic Biol Med 2013;65:952-968.
38. Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, Kaul MG, Tromsdorf UI, Weller H, Waurisch C, Eychmüller A, Gordts PL, Rinninger F, Bruegelmann K, Freund B, Nielsen P, Merkel M, Heeren J. Brown adipose tissue activity controls triglyceride clearance. Nat Med 2011;17(2):200-205.
39. Li Y, Yang P, Zhao L, Chen Y, Zhang X, Zeng S, Wei L, Varghese Z, Moorhead JF, Chen Y, Ruan XZ. CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway. J Lipid Res 2019;60(4):844-855.
40. Quintero P, González-Muniesa P, García-Díaz DF, Martínez JA. Effects of hyperoxia exposure on metabolic markers and gene expression in 3T3-L1 adipocytes. J Physiol Biochem 2012;68(4):663-669.
41. Quintero P, Gonzalez-Muniesa P, Martinez JA. Influence of different oxygen supply on metabolic markers and gene response in murine adipocytes. J Biol Regul Homeost Agents 2012;26(3):379-388.
42. Shan L, Yu XC, Liu Z, Hu Y, Sturgis LT, Miranda ML, Liu Q. The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms. J Biol chem 2009;284(3):1419-1424.
43. Biterova E, Esmaeeli M, Alanen HI, Saaranen M, Ruddock LW. Structures of Angptl3 and Angptl4, modulators of triglyceride levels and coronary artery disease. Sci Rep 2018;8(1).
44. Kim KH, Kim YH, Son JE, Lee JH, Kim S, Choe MS, Moon JH, Zhong J, Fu K, Lenglin F, Yoo JA, Bilan PJ, Klip A, Nagy A, Kim JR, Park JG, Hussein SM, Doh KO, Hui CC, Sung HK. Intermittent fasting promotes adipose thermogenesis and metabolic homeostasis via VEGF-mediated alternative activation of macrophage. Cell Res 2017;27(11):1309-1326.
45. Li G, Xie C, Lu S, Nichols R G, Tian Y, Li L, Patel D, Ma Y, Brocker CN, Yan T, Krausz KW, Xiang R, Gavrilova O, Patterson AD, Gonzalez FJ. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota. Cell Metab 2017;26(4):672-685.
46. Novikoff AB, Novikoff PM. Microperoxisomes and peroxisomes in relation to lipid metabolism. Ann N Y Acad Sci 1982;386:138-152.
47. Novikoff AB, Novikoff PM, Rosen OM, Rubin CS. Organelle relationships in cultured 3T3-L1 preadipocytes. J Cell Biol 1980;87(1):180-196.
48. Pavelka M, Goldenberg H, Hüttinger M, Kramar R. Enzymic and morphological studies on catalase positive particles from brown fat of cold adapted rats. Histochemistry 1976;50(1):47-55.
49. Kong J, Ji Y, Jeon YG, Han JS, Han KH, Lee JH, Lee G, Jang H, Choe SS, Baes M, Kim JB. Spatiotemporal contact between peroxisomes and lipid droplets regulates fasting-induced lipolysis via PEX5. Nat Commun 2020;11(1).
50. Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ. Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest 2019;129(2):694-711.
51. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957;226(1):497-509.