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Research article
The Characteristics of Patients with Subsequent Distal Radius Fracture After Initial Distal Radius Fracture
Young Ho Shin
Asan Medical Center
Corresponding Author
ORCiD: https://orcid.org/0000-0002-9388-9720
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The characteristics of patients who experienced subsequent distal radius fracture (DRF) after initial DRF have not been determined. The purpose of this study was to investigate the characteristics of patients with subsequent DRF and to compare bone fragility parameters of patients with primary and subsequent distal DRF.
Methods: We compared demographic characteristics and bone fragility parameters, including bone mineral densities (BMDs), trabecular bone score (TBS), hip geometry parameters, and bicortical thickness (BCT) of the distal radius in 215 patients with initial DRF and 26 patients with subsequent DRF. To reduce bias, patients with subsequent DRF were propensity score-matched in a 1:2 manner with patients affected by initial DRF, and additional comparison was performed.
Results: Patients in the subsequent DRF group were older than those in the initial DRF group, but this difference was not significant (p = 0.091). The proportion of patients receiving osteoporosis medications was significantly higher in the subsequent DRF group (41.7% vs. 19.2%, p = 0.011). Bone fragility parameters, including BMD, TBS, hip geometry parameters, and BCT did not differ significantly between the two groups. However, ten-year probability of major osteoporotic fractures was significantly higher in patients with subsequent DRF (p < 0.001). Similar results were observed upon comparing the propensity score-matched initial and subsequent DRF groups.
Conclusions: These findings suggest that the occurrence of subsequent DRF after initial DRF can be attributed to multiple factors rather than bone fragility alone. Systematic and multidisciplinary managements would be helpful for preventing the occurrence of subsequent DRF after initial DRF.
Keywords
Distal radius fracture, Subsequent Fracture, Bone mineral density, Hip geometry, Trabecular bone score, Bicortical thickness
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This is a preprint. It has not completed peer review.
Research article
The Characteristics of Patients with Subsequent Distal Radius Fracture After Initial Distal Radius Fracture
Young Ho Shin
Asan Medical Center
Corresponding Author
ORCiD: https://orcid.org/0000-0002-9388-9720
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 18 Sep, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The characteristics of patients who experienced subsequent distal radius fracture (DRF) after initial DRF have not been determined. The purpose of this study was to investigate the characteristics of patients with subsequent DRF and to compare bone fragility parameters of patients with primary and subsequent distal DRF.
Methods: We compared demographic characteristics and bone fragility parameters, including bone mineral densities (BMDs), trabecular bone score (TBS), hip geometry parameters, and bicortical thickness (BCT) of the distal radius in 215 patients with initial DRF and 26 patients with subsequent DRF. To reduce bias, patients with subsequent DRF were propensity score-matched in a 1:2 manner with patients affected by initial DRF, and additional comparison was performed.
Results: Patients in the subsequent DRF group were older than those in the initial DRF group, but this difference was not significant (p = 0.091). The proportion of patients receiving osteoporosis medications was significantly higher in the subsequent DRF group (41.7% vs. 19.2%, p = 0.011). Bone fragility parameters, including BMD, TBS, hip geometry parameters, and BCT did not differ significantly between the two groups. However, ten-year probability of major osteoporotic fractures was significantly higher in patients with subsequent DRF (p < 0.001). Similar results were observed upon comparing the propensity score-matched initial and subsequent DRF groups.
Conclusions: These findings suggest that the occurrence of subsequent DRF after initial DRF can be attributed to multiple factors rather than bone fragility alone. Systematic and multidisciplinary managements would be helpful for preventing the occurrence of subsequent DRF after initial DRF.