DOI: https://doi.org/10.21203/rs.3.rs-714922/v1
Purpose: To evaluate the risk factors of miscarriage in patients attempted cervical polypectomy during the first and second trimester pregnancy.
Methods: Pregnant women with singleton infants who underwent cervical polypectomy during the first and second trimester between January 2013 to May 2019 were investigated. The study retrospectively reviewed the clinical features and pregnancy outcomes after cervical polypectomy. A multivariable regression was performed to predict the risk factors of miscarriage.
Results: A total of 307 pregnant females were eventually included in our study. 27 patients (8.8%, 27/307) had a miscarriage before 28 weeks, 37 patients (12.1%, 37/307) had a preterm delivery. After univariate analysis, we found that the presence of decidual polyps and vaginal bleeding after polypectomy were the risk factors for miscarriage. Moreover, the incidence of miscarriage was significantly higher in the patients with decidual polyps than in those with endocervical polyps (14.9% vs.5.6%, p=0.010).
Conclusion: The most suitable hemostasis method should be taken in the cervical polypectomy during pregnancy. The risk of miscarriage associated with polypectomy during pregnancy is higher in females with decidual polyps. If they do not cause excessive vaginal bleeding and can be ruled out the possibility of malignancy, conservative treatment may lead to a better outcome.
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