This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Nan Liu
Chongqing University
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
Background and Objective
To decrease the risk of complications of inguinal lymphadenectomy by investigating the value of low CO2 pressure video endoscopic inguinal lymphadenectomy in the treatment of penile cancer.
Methods
The clinical data of a total of 44 patients who underwent video endoscopic inguinal lymphadenectomy (VEIL) were collected for statistical analysis.
Results
The average operation time was ( 106.88 ± 17.93) min in low CO2 pressure (LP) group and ( 115.79 ± 20.29) min in normal CO2 pressure (NP) group. The average number of lymph nodes was (10.83 ± 2.14) in LP group and (11.16 ± 1.77) ml in NP group. The intraoperative PaCO2 value was (45.51 ± 4.57) mmHg in LP group and (50.77 ± 6.50) ml in NP group. The PH value of blood gas analysis was (7.35 ± 0.05) in LP group and (7.31 ± 0.04) ml in NP group. The incidence of emphysema was 2/25 in LP group while it was 9/19 in NP group. 2 cases of skin metastasis and 1 lung metastasis were observed in NP group, but not in LP group.
Conclusions
Decrease of CO2 pressure during operation will not increase the difficulty of the surgery. LP VEIL can reduce the risk of complications including hypercapnia and the subcutaneous or lung recurrence.
Keywords
Penile cancer, Lymph node excision, Laparoscopy
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Nan Liu
Chongqing University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 17 Sep, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Oncology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background and Objective
To decrease the risk of complications of inguinal lymphadenectomy by investigating the value of low CO2 pressure video endoscopic inguinal lymphadenectomy in the treatment of penile cancer.
Methods
The clinical data of a total of 44 patients who underwent video endoscopic inguinal lymphadenectomy (VEIL) were collected for statistical analysis.
Results
The average operation time was ( 106.88 ± 17.93) min in low CO2 pressure (LP) group and ( 115.79 ± 20.29) min in normal CO2 pressure (NP) group. The average number of lymph nodes was (10.83 ± 2.14) in LP group and (11.16 ± 1.77) ml in NP group. The intraoperative PaCO2 value was (45.51 ± 4.57) mmHg in LP group and (50.77 ± 6.50) ml in NP group. The PH value of blood gas analysis was (7.35 ± 0.05) in LP group and (7.31 ± 0.04) ml in NP group. The incidence of emphysema was 2/25 in LP group while it was 9/19 in NP group. 2 cases of skin metastasis and 1 lung metastasis were observed in NP group, but not in LP group.
Conclusions
Decrease of CO2 pressure during operation will not increase the difficulty of the surgery. LP VEIL can reduce the risk of complications including hypercapnia and the subcutaneous or lung recurrence.
Figure 1
Figure 2
Figure 3
Figure 4
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