This paper represents sample results for the C2 and C3 modules of the MAS. Genomic index maps were generated for SARS-CoV-2 genomes from different samples worldwide, and eleven other viral genomes were selected for comparisons. Each 2D genomic index map acts as a pair of X-Y coordinate scatter points located in a specific geometric region restricted. Supported by the principle of entropy invariance and visual distributions, it is convenient to identify the variations of SARS-CoV-2 genomes in the global scope. In view of this powerful transformation structure, future exploration of the detailed systematic expansion of theory and medical applications for COVID-19 patients is required.