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Low Incidence of Venous Thrombosis But High Incidence of Arterial Thrombotic Complications Among Critically Ill COVID-19 Patients in Singapore
Eng Soo Yap
Khoo Teck Puat Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0002-7910-3154
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This work is licensed under a CC BY 4.0 License. Read Full License
Background: Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients.
Method and Results: This is a national multicenter retrospective observational study involving all consecutive adult COVID-19 patients who required intensive care units (ICU) admission between 23 January 2020 and 30 April 2020 in Singapore. 111 patients were included and the venous and arterial thrombotic rates in ICU were 1.8% (n=2) and 9.9% (n=11), respectively. Major bleeding rate was 14.8% (n=16).
Conclusions: Critically ill COVID-19 patients in Singapore have lower venous thromboembolism but higher arterial thrombosis rates and bleeding manifestations than other reported cohorts.
Keywords
COVID-19, thrombosis, critical care
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CURRENT STATUS: Under Review
Version 1
Posted 25 Sep, 2020
No community comments so far
Review #2 received
Received 27 Dec, 2020
Reviewer #2 agreed
On 20 Dec, 2020
Review #1 received
Received 08 Dec, 2020
Reviewer #1 agreed
On 17 Nov, 2020
Reviewers invited
Invitations sent on 04 Nov, 2020
Editor assigned
On 14 Sep, 2020
First submitted
On 13 Sep, 2020
Submission checks complete
On 13 Sep, 2020
Editor invited
On 13 Sep, 2020
Metrics
Comments: 0
PDF Downloads: ...
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Subject Areas
Critical Care & Emergency Medicine
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This preprint is under consideration at Thrombosis Journal. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Low Incidence of Venous Thrombosis But High Incidence of Arterial Thrombotic Complications Among Critically Ill COVID-19 Patients in Singapore
Eng Soo Yap
Khoo Teck Puat Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0002-7910-3154
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 25 Sep, 2020
No community comments so far
Review #2 received
Received 27 Dec, 2020
Reviewer #2 agreed
On 20 Dec, 2020
Review #1 received
Received 08 Dec, 2020
Reviewer #1 agreed
On 17 Nov, 2020
Reviewers invited
Invitations sent on 04 Nov, 2020
Editor assigned
On 14 Sep, 2020
First submitted
On 13 Sep, 2020
Submission checks complete
On 13 Sep, 2020
Editor invited
On 13 Sep, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Critical Care & Emergency Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Arterial and venous thrombosis are reported to be common in critically ill COVID-19 patients.
Method and Results: This is a national multicenter retrospective observational study involving all consecutive adult COVID-19 patients who required intensive care units (ICU) admission between 23 January 2020 and 30 April 2020 in Singapore. 111 patients were included and the venous and arterial thrombotic rates in ICU were 1.8% (n=2) and 9.9% (n=11), respectively. Major bleeding rate was 14.8% (n=16).
Conclusions: Critically ill COVID-19 patients in Singapore have lower venous thromboembolism but higher arterial thrombosis rates and bleeding manifestations than other reported cohorts.